Triborheological Analysis of Reconstituted Gastrointestinal Mucus/Chitosan:TPP Nanoparticles System to Study Mucoadhesion Phenomenon under Different pH Conditions

Triborheological Analysis of Reconstituted Gastrointestinal Mucus/Chitosan:TPP Nanoparticles System to Study Mucoadhesion Phenomenon under Different pH Conditions

Polymeric nanoparticles have attracted much attention as pharmaceutical delivery vehicles to prolong residence time and enhance the bioavailability of therapeutic molecules through the mucoadhesive phenomenon. In this study, chitosan:TPP nanoparticles were synthetized using the ionic gelation techni...

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Bibliographic Details
Main Authors: Gustavo Ruiz-Pulido, David Quintanar-Guerrero, Luis Eduardo Serrano-Mora, Dora I. Medina
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Polymers
Subjects:
rheological synergism
mucoadhesion
reconstituted mucus
chitosan:TPP nanoparticles
gastrointestinal pH
Online Access:https://www.mdpi.com/2073-4360/14/22/4978

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