Resistência ao tratamento no linfoma de Burkitt: associação com mutações específicas no gene TP53? Treatment resistance in Burkitt's lymphoma: is it associated with specific mutations of the TP53 gene?
O linfoma de Burkitt (LB) surge a partir de uma célula do centro germinativo que perde o controle da proliferação devido à ativação do gene c-myc. A resistência à apoptose é uma causa importante da falha à quimioterapia na maioria dos cânceres e também no LB. A taxa alta de apoptose observada no LB...
প্রধান লেখক: | Eliane P. S. Magluta, Claudete E. Klumb |
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বিন্যাস: | প্রবন্ধ |
ভাষা: | English |
প্রকাশিত: |
Elsevier
2008-02-01
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মালা: | Revista Brasileira de Hematologia e Hemoterapia |
বিষয়গুলি: | |
অনলাইন ব্যবহার করুন: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000100011 |
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