A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity.

A global census of fission yeast deubiquitinating enzyme localization and interaction networks reveals distinct compartmentalization profiles and overlapping functions in endocytosis and polarity.

Ubiquitination and deubiquitination are reciprocal processes that tune protein stability, function, and/or localization. The removal of ubiquitin and remodeling of ubiquitin chains is catalyzed by deubiquitinating enzymes (DUBs), which are cysteine proteases or metalloproteases. Although ubiquitinat...

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Bibliographic Details
Main Authors: Ilektra Kouranti, Janel R McLean, Anna Feoktistova, Ping Liang, Alyssa E Johnson, Rachel H Roberts-Galbraith, Kathleen L Gould
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2935449?pdf=render

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