Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos
<p><strong>Background</strong>: Preeclampsia is the main cause of morbidity, mortality, maternal and perinatal disability, making its diagnosis and prevention important.<br /><strong>Objective</strong>: to validate the predictive value of the angiogenic test (sFlt...
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| Format: | Article |
| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2020-08-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/4403 |
| _version_ | 1797277814899081216 |
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| author | Vivian Rosa Vázquez Martínez Cristóbal Jorge Torres González Greter Torres Vázquez |
| author_facet | Vivian Rosa Vázquez Martínez Cristóbal Jorge Torres González Greter Torres Vázquez |
| author_sort | Vivian Rosa Vázquez Martínez |
| collection | DOAJ |
| description | <p><strong>Background</strong>: Preeclampsia is the main cause of morbidity, mortality, maternal and perinatal disability, making its diagnosis and prevention important.<br /><strong>Objective</strong>: to validate the predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy.<br /><strong>Methods</strong>: a descriptive cross-sectional study was carried out at the Gynecology and Obstetrics Service, Dr. Gustavo Aldereguía Lima Hospital, Cienfuegos, from January 2017 to December 2018. 125 pregnant women with suspected pre-eclampsia, from the Total number of patients admitted with high blood pressure were studied. They were divided into two groups according to the diagnostic values of the Roche angiogenic test (sFlt / PIGF ratio), and perinatal results and maternal complications were compared. The Chi square statistic (p <0.05) was used and the risk ratio (95% CI) was calculated.<br /><strong>Results</strong>: the angiogenic test was positive more frequently in those pregnant women who developed eclampsia preeclamsia, with 90.7% vs. 9.3% in those who did not develop eclampsia preeclamsia (p = 0.000); as well as those less than 34 weeks of gestational age who developed pre-eclampsia (72%), with high sensitivity and specificity. The use of the test in the follow-up of the patients was associated with a tendency to prolong the pregnancy. Its positivity was more related to maternal, fetal and neonatal complications.<br /><strong>Conclusion</strong>: a positive value of the test implies an increased risk of developing preeclamsia eclampsia and maternal complications, as well as adverse perinatal results. The angiogenic test showed utility in the diagnosis and prognosis of the disease.</p> |
| first_indexed | 2024-03-07T15:54:44Z |
| format | Article |
| id | doaj.art-e4eb879cffec4815a7a0bf17320c5dae |
| institution | Directory Open Access Journal |
| issn | 1727-897X |
| language | Spanish |
| last_indexed | 2024-03-07T15:54:44Z |
| publishDate | 2020-08-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj.art-e4eb879cffec4815a7a0bf17320c5dae2024-03-04T23:09:50ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2020-08-011846656741873Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in CienfuegosVivian Rosa Vázquez Martínez0Cristóbal Jorge Torres González1Greter Torres Vázquez2Universidad de Ciencias Médicas de Cienfuegos. CienfuegosHospital General Universitario Dr. Gustavo Aldereguía Lima. CienfuegosUnivesidad de Cienfuegos. Cienfuegos<p><strong>Background</strong>: Preeclampsia is the main cause of morbidity, mortality, maternal and perinatal disability, making its diagnosis and prevention important.<br /><strong>Objective</strong>: to validate the predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy.<br /><strong>Methods</strong>: a descriptive cross-sectional study was carried out at the Gynecology and Obstetrics Service, Dr. Gustavo Aldereguía Lima Hospital, Cienfuegos, from January 2017 to December 2018. 125 pregnant women with suspected pre-eclampsia, from the Total number of patients admitted with high blood pressure were studied. They were divided into two groups according to the diagnostic values of the Roche angiogenic test (sFlt / PIGF ratio), and perinatal results and maternal complications were compared. The Chi square statistic (p <0.05) was used and the risk ratio (95% CI) was calculated.<br /><strong>Results</strong>: the angiogenic test was positive more frequently in those pregnant women who developed eclampsia preeclamsia, with 90.7% vs. 9.3% in those who did not develop eclampsia preeclamsia (p = 0.000); as well as those less than 34 weeks of gestational age who developed pre-eclampsia (72%), with high sensitivity and specificity. The use of the test in the follow-up of the patients was associated with a tendency to prolong the pregnancy. Its positivity was more related to maternal, fetal and neonatal complications.<br /><strong>Conclusion</strong>: a positive value of the test implies an increased risk of developing preeclamsia eclampsia and maternal complications, as well as adverse perinatal results. The angiogenic test showed utility in the diagnosis and prognosis of the disease.</p>http://medisur.sld.cu/index.php/medisur/article/view/4403preeclampsiahipertensión inducida en el embarazocomplicaciones del embarazo |
| spellingShingle | Vivian Rosa Vázquez Martínez Cristóbal Jorge Torres González Greter Torres Vázquez Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos Medisur preeclampsia hipertensión inducida en el embarazo complicaciones del embarazo |
| title | Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos |
| title_full | Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos |
| title_fullStr | Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos |
| title_full_unstemmed | Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos |
| title_short | Predictive value of the angiogenic test (sFlt / PIGF ratio) in hypertensive disorders of pregnancy. Perinatal results in Cienfuegos |
| title_sort | predictive value of the angiogenic test sflt pigf ratio in hypertensive disorders of pregnancy perinatal results in cienfuegos |
| topic | preeclampsia hipertensión inducida en el embarazo complicaciones del embarazo |
| url | http://medisur.sld.cu/index.php/medisur/article/view/4403 |
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