Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics
Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, characterized by diffuse mucosal inflammation with bloody diarrhea. The therapeutic goals in UC have evolved from symptomatic relief to deep remission, including sustained steroid-free clinical remission, mucosal healing, and...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2018-04-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.4.192 |
| _version_ | 1818479071211814912 |
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| author | Jung Ho Bae Dong-Hoon Yang |
| author_facet | Jung Ho Bae Dong-Hoon Yang |
| author_sort | Jung Ho Bae |
| collection | DOAJ |
| description | Ulcerative colitis (UC) is a chronic inflammatory condition of the colon, characterized by diffuse mucosal inflammation with bloody diarrhea. The therapeutic goals in UC have evolved from symptomatic relief to deep remission, including sustained steroid-free clinical remission, mucosal healing, and ideally histologic remission. The management of UC has significantly been improved by advance of biologic agents including anti-tumor necrosis factor alpha (TNF-α) antibodies. Anti-TNF-α agent have progressively been introduced earlier in treatment algorithms for UC in order to minimize steroid exposure and dependence and to maximize disease control and quality of life. We reviewed the therapeutic recommendations of biologic agents for UC in the Korean and European Crohn’s and Colitis Organization guidelines. |
| first_indexed | 2024-12-10T09:56:23Z |
| format | Article |
| id | doaj.art-e4eccafe189641898552c8791cfe4361 |
| institution | Directory Open Access Journal |
| issn | 1598-9992 |
| language | English |
| last_indexed | 2024-12-10T09:56:23Z |
| publishDate | 2018-04-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-e4eccafe189641898552c8791cfe43612022-12-22T01:53:30ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922018-04-0171419219510.4166/kjg.2018.71.4.192kjg.2018.71.4.192Comparison of Treatment Guidelines for Ulcerative Colitis: Role of BiologicsJung Ho Bae0Dong-Hoon Yang1Department of Internal Medicine, Healthcare System Gangnam Center, Seoul National University Hospital, Seoul, KoreaDepartment of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, KoreaUlcerative colitis (UC) is a chronic inflammatory condition of the colon, characterized by diffuse mucosal inflammation with bloody diarrhea. The therapeutic goals in UC have evolved from symptomatic relief to deep remission, including sustained steroid-free clinical remission, mucosal healing, and ideally histologic remission. The management of UC has significantly been improved by advance of biologic agents including anti-tumor necrosis factor alpha (TNF-α) antibodies. Anti-TNF-α agent have progressively been introduced earlier in treatment algorithms for UC in order to minimize steroid exposure and dependence and to maximize disease control and quality of life. We reviewed the therapeutic recommendations of biologic agents for UC in the Korean and European Crohn’s and Colitis Organization guidelines.http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.4.192Ulcerative colitisTumor necrosis factor-alphaBiological products |
| spellingShingle | Jung Ho Bae Dong-Hoon Yang Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics The Korean Journal of Gastroenterology Ulcerative colitis Tumor necrosis factor-alpha Biological products |
| title | Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics |
| title_full | Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics |
| title_fullStr | Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics |
| title_full_unstemmed | Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics |
| title_short | Comparison of Treatment Guidelines for Ulcerative Colitis: Role of Biologics |
| title_sort | comparison of treatment guidelines for ulcerative colitis role of biologics |
| topic | Ulcerative colitis Tumor necrosis factor-alpha Biological products |
| url | http://www.kjg.or.kr/journal/view.html?doi=10.4166/kjg.2018.71.4.192 |
| work_keys_str_mv | AT junghobae comparisonoftreatmentguidelinesforulcerativecolitisroleofbiologics AT donghoonyang comparisonoftreatmentguidelinesforulcerativecolitisroleofbiologics |