Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients

AIM: To evaluate inter-device agreement of anterior keratometry obtained by the IOLMaster® 500 and Pentacam® HR in type 2 diabetic and non-diabetic patients. METHODS: Corneal measurements were sequentially performed in 60 diabetes mellitus (DM) and 48 age and sex-matched controls undergoing catarac...

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Main Authors: João N Beato, João Esteves-Leandro, David Reis, Rita Matos, Manuel Falcão, Vítor Rosas, Ângela Carneiro, Fernando Falcão-Reis
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2020-06-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://ies.ijo.cn/en_publish/2020/6/20200610.pdf
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author João N Beato
João Esteves-Leandro
David Reis
Rita Matos
Manuel Falcão
Vítor Rosas
Ângela Carneiro
Fernando Falcão-Reis
author_facet João N Beato
João Esteves-Leandro
David Reis
Rita Matos
Manuel Falcão
Vítor Rosas
Ângela Carneiro
Fernando Falcão-Reis
author_sort João N Beato
collection DOAJ
description AIM: To evaluate inter-device agreement of anterior keratometry obtained by the IOLMaster® 500 and Pentacam® HR in type 2 diabetic and non-diabetic patients. METHODS: Corneal measurements were sequentially performed in 60 diabetes mellitus (DM) and 48 age and sex-matched controls undergoing cataract surgery. Variables recorded included flat and steep keratometry, mean keratometry (Km), astigmatism magnitude, axis location, J0 and J45 components. Bland-Altman plots and intraclass correlation coefficients were used for examination of agreement. Subgroup analyses were performed for astigmatism magnitude, diabetes duration, hemoglobin A1c (HbA1c) levels and diabetic retinopathy (DR) stage. RESULTS: Agreement for Km and astigmatism magnitude were considered good and moderate, with 95% limits of agreement (LoA) of -1.09 to 1.23 diopters (D) and -0.83 to 0.86 D in DM group, respectively; and -0.59 to 0.72 D and -0.98 to 0.75 D in non-DM group, respectively. In contrast, the 95% LoA for corneal axis exceeded the clinically relevant margins in both groups. In the total sample, only 41 eyes (38%) had a smaller than 5-degree difference. Diabetes duration, HbA1c levels and DR stage were not found to significantly affect agreement. Logistic regression showed that higher corneal power (P=0.021) and astigmatism magnitude (P=0.011) were associated with a decreased risk of having a difference in axis location greater than 10-degrees. CONCLUSION: In both groups, IOLMaster and Pentacam agree well for corneal power and moderately for astigmatism. However, axis location disagreement is frequent in eyes with flatter corneas and small amounts of astigmatism.
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spelling doaj.art-e4f183f61708461cb031adac8376d06a2022-12-22T01:34:00ZengPress of International Journal of Ophthalmology (IJO PRESS)International Journal of Ophthalmology2222-39592227-48982020-06-0113692092610.18240/ijo.2020.06.10Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patientsJoão N Beato0João Esteves-Leandro1David Reis2Rita Matos3Manuel Falcão4Vítor Rosas5Ângela Carneiro6Fernando Falcão-Reis7Department of Ophthalmology, São João Hospital, Porto 4200-319, Portugal; Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, PortugalFaculty of Medicine, University of Porto, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, Portugal; Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, Portugal; Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalDepartment of Ophthalmology, São João Hospital, Porto 4200-319, Portugal; Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto 4200-319, PortugalAIM: To evaluate inter-device agreement of anterior keratometry obtained by the IOLMaster® 500 and Pentacam® HR in type 2 diabetic and non-diabetic patients. METHODS: Corneal measurements were sequentially performed in 60 diabetes mellitus (DM) and 48 age and sex-matched controls undergoing cataract surgery. Variables recorded included flat and steep keratometry, mean keratometry (Km), astigmatism magnitude, axis location, J0 and J45 components. Bland-Altman plots and intraclass correlation coefficients were used for examination of agreement. Subgroup analyses were performed for astigmatism magnitude, diabetes duration, hemoglobin A1c (HbA1c) levels and diabetic retinopathy (DR) stage. RESULTS: Agreement for Km and astigmatism magnitude were considered good and moderate, with 95% limits of agreement (LoA) of -1.09 to 1.23 diopters (D) and -0.83 to 0.86 D in DM group, respectively; and -0.59 to 0.72 D and -0.98 to 0.75 D in non-DM group, respectively. In contrast, the 95% LoA for corneal axis exceeded the clinically relevant margins in both groups. In the total sample, only 41 eyes (38%) had a smaller than 5-degree difference. Diabetes duration, HbA1c levels and DR stage were not found to significantly affect agreement. Logistic regression showed that higher corneal power (P=0.021) and astigmatism magnitude (P=0.011) were associated with a decreased risk of having a difference in axis location greater than 10-degrees. CONCLUSION: In both groups, IOLMaster and Pentacam agree well for corneal power and moderately for astigmatism. However, axis location disagreement is frequent in eyes with flatter corneas and small amounts of astigmatism.http://ies.ijo.cn/en_publish/2020/6/20200610.pdfkeratometrydiabetes mellitusastigmatismcataractdiabetic retinopathy
spellingShingle João N Beato
João Esteves-Leandro
David Reis
Rita Matos
Manuel Falcão
Vítor Rosas
Ângela Carneiro
Fernando Falcão-Reis
Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
International Journal of Ophthalmology
keratometry
diabetes mellitus
astigmatism
cataract
diabetic retinopathy
title Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
title_full Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
title_fullStr Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
title_full_unstemmed Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
title_short Agreement between IOLMaster® 500 and Pentacam® HR for keratometry assessment in type 2 diabetic and non-diabetic patients
title_sort agreement between iolmaster r 500 and pentacam r hr for keratometry assessment in type 2 diabetic and non diabetic patients
topic keratometry
diabetes mellitus
astigmatism
cataract
diabetic retinopathy
url http://ies.ijo.cn/en_publish/2020/6/20200610.pdf
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