The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases: a review

The use of biodiversity as source of new chemical entities against defined molecular targets for treatment of malaria, tuberculosis, and T-cell mediated diseases: a review

The modern approach to the development of new chemical entities against complex diseases, especially the neglected endemic diseases such as tuberculosis and malaria, is based on the use of defined molecular targets. Among the advantages, this approach allows (i) the search and identification of lead...

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Bibliographic Details
Main Authors: Luiz Augusto Basso, Luiz Hildebrando Pereira da Silva, Arthur Germano Fett-Neto, Walter Filgueira de Azevedo Junior, Ícaro de Souza Moreira, Mário Sérgio Palma, João Batista Calixto, Spartaco Astolfi Filho, Ricardo Ribeiro dos Santos, Milena Botelho Pereira Soares, Diógenes Santiago Santos
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2005-10-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
biodiversity
defined molecular targets
tuberculosis
Apicomplexan
T-cell mediated diseases
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000600001&lng=en&tlng=en

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