Comprehensive Steroid Assay with Non-Targeted Analysis Using Liquid Chromatography Ion Mobility Mass Spectrometry

Comprehensive Steroid Assay with Non-Targeted Analysis Using Liquid Chromatography Ion Mobility Mass Spectrometry

Aldosterone-producing adenomas (APAs) have different steroid profiles in serum, depending on the causative genetic mutation. Ion mobility is a separation technique for gas-phase ions based on their <i>m</i>/<i>z</i> values, shapes, and sizes. Human serum (100 µL) was purified...

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Bibliographic Details
Main Authors: Mai Yamakawa, Shigehiro Karashima, Riko Takata, Taichi Haba, Keigo Kuroiwa, Hideaki Touyama, Atsushi Hashimoto, Seigo Konishi, Daisuke Aono, Mitsuhiro Kometani, Hidetaka Nambo, Takashi Yoneda, Issey Osaka
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
steroid
aldosterone
quantitation
non-target
ion mobility
LC/IM/MS
Online Access:https://www.mdpi.com/1422-0067/23/22/13858

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