Predicting molecular mechanism of silymarin-potentiated diclofenac toxicity: Insight from in silico molecular docking

Silymarin was shown to enhance diclofenac toxicity by inducing the loss of mitochondrial membrane permeability (MMP) in Caco-2 cells, independent of endoplasmic reticulum stress. This study employed in silico molecular docking to further investigate the potential interaction between silymarin and sp...

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Bibliographic Details
Main Authors: Cherdsak Boonyong, Suree Jianmongkol
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Toxicology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750023001130