$Positive response to niraparib in chemo-refractory patients with metastatic appendiceal mucinous adenocarcinoma harboring ATM mutations: A case report$

Positive response to niraparib in chemo-refractory patients with metastatic appendiceal mucinous adenocarcinoma harboring ATM mutations: A case report

BackgroundAppendiceal mucinous adenocarcinoma, one kind of specific colorectal cancer, is lowly prevalent and rarely diagnosed in clinical practice. In addition, there have been limited standard treatment strategies established for patients with appendiceal mucinous adenocarcinoma, especially with m...

Full description

Bibliographic Details
Main Authors:	Junhui Wang, Huijuan He, Wansu Xu, Jianxin Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-02-01
Series:	Frontiers in Oncology
Subjects:	niraparib chemo-refractory appendiceal mucinous adenocarcinoma ataxia-telangiectasia mutated (ATM) homologous recombination deficiency
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1010871/full

Similar Items

Appendiceal Mucinous Tumor Presenting as Recurrent Bowel Obstruction
by: Wei-Tang Lin, et al.
Published: (2022-11-01)

High-grade appendiceal mucinous neoplasm presenting as a giant appendiceal mucocele
by: Alan Lu, BA, et al.
Published: (2021-05-01)

Clinicopathological Characteristics of Primary Appendiceal Mucinous Neoplasm and Recurrence After Radical Resection
by: Zaibiao Wang, et al.
Published: (2022-05-01)

A retrospective analysis and literature review of neoplastic appendiceal mucinous lesions
by: Belén Matias-García, et al.
Published: (2021-02-01)

Clinical complications and their management in a child with ataxia‐telangiectasia (A‐T): A case report study
by: Marzieh Heidarzadeh Arani, et al.
Published: (2021-01-01)

Rare Cases of Low-Grade Appendiceal Mucinous Neoplasm: Two Case Reports and a Literature Review
by: Senichiro Yanagawa, et al.
Published: (2019-06-01)

Survival and Functional Immune Reconstitution After Haploidentical Stem Cell Transplantation in Atm-Deficient Mice
by: Ruth Pia Duecker, et al.
Published: (2021-06-01)

Atypical ATMs: Broadening the phenotypic spectrum of ATM-associated hereditary cancer
by: Nicholas A. Borja, et al.
Published: (2023-02-01)

Appendiceal tumors in patients undergoing primary surgery for mucinous ovarian tumors in a tertiary hospital, in Southern Thailand
by: Kulisara Nanthamongkolkul, et al.
Published: (2022-07-01)

Two novel heterozygote mutations of ATM in a Chinese family with dystonia-dominant ataxia telangiectasia and literature review
by: Zhi-Jun Liu, et al.
Published: (2023-03-01)

Appendiceal mucinous neoplasm, a rare diagnosis within gastrointestinal tumors. Case report
by: Daniela Suárez-Velázquez, et al.
Published: (2022-01-01)

Incidental detection of low-grade appendiceal mucinous neoplasm
by: Archana Chirag Buch, et al.
Published: (2023-01-01)

ATM splicing variants as biomarkers for low dose dexamethasone treatment of A-T
by: Michele Menotta, et al.
Published: (2017-07-01)

Preoperative Diagnosis and Surgical Approach of Appendiceal Mucinous Cystadenoma: Usefulness of Volcano Sign
by: Masahiro Shiihara, et al.
Published: (2017-09-01)

Analysis of Clinical and Genetic Characterization of Three Ataxia–Telangiectasia Pedigrees With Novel ATM Gene Mutations
by: Peng Huang, et al.
Published: (2022-05-01)

Massive appendiceal mucinous neoplasm diagnosed after abdominal trauma: Pitfalls in imaging and diagnosis
by: Wanyang Qian, MD, et al.
Published: (2024-05-01)

Survival outcomes of appendiceal mucinous neoplasms by histological type and stage: Analysis of 266 cases in a multicenter collaborative retrospective clinical study
by: Toshinori Sueda, et al.
Published: (2019-05-01)

Misdiagnosed appendiceal mucinous neoplasms and primary ovarian mucinous tumors present with different pre- and intraoperative characteristics
by: Yi Yu, et al.
Published: (2022-08-01)

Giant mucinous adenocarcinoma of the appendix: a case report
by: Sheng-Chun Dang, et al.
Published: (2017-07-01)

A case of Endometrioid endometrial adenocarcinoma with synchronous low-grade Appendiceal mucinous neoplasm and Pseudomyxoma peritonei
by: Shweta Raje, et al.
Published: (2021-01-01)

Ataxia-telangiectasia in China: a case report of a novel ATM variant and literature review
by: Li Shao, et al.
Published: (2023-07-01)

Appendiceal Mucinous Neoplasms and Inflammatory Bowel Disease: Systematic Review of the Literature
by: Alessandro Michele Bonomi, et al.
Published: (2023-12-01)

Clinicopathological Features of Low-Grade Appendiceal Mucinous Neoplasms Confined to the Appendix
by: Yiyan Lu, et al.
Published: (2021-07-01)

Significance of the Entire Appendiceal Evaluation in the Diagnosis of Serrated Lesions, Low-Grade Appendiceal Mucinous Neoplasm, and Appendiceal Diverticulosis Disease
by: Fang Li, et al.
Published: (2022-01-01)

Appendiceal Mucinous Neoplasms: From Clinic to Pathology and Prognosis
by: Luis González Bayón, et al.
Published: (2023-06-01)

Case Report: An Unusual Case of Pulmonary Metastatic Adenocarcinoma From Low-Grade Appendiceal Mucinous Neoplasms
by: Xin-Yu Zhao, et al.
Published: (2022-07-01)

Salvage hyperthermic intraperitoneal chemotherapy for appendiceal mucinous adenocarcinoma with peritoneal mucinous carcinomatosis
by: Sheng-Cheng Wu, et al.
Published: (2018-03-01)

Severe reaction to radiotherapy provoked by hypomorphic germline mutations in ATM (ataxia–telangiectasia mutated gene)
by: Reza Asadollahi, et al.
Published: (2020-10-01)

ATM polymorphisms IVS24-9delT, IVS38-8T>C, and 5557G>A in Mexican women with familial and/or early-onset breast cancer
by: Fabiola del Carmen Calderón-Zúñiga, et al.
Published: (2014-03-01)

The value of ultrasound combined with CT in identifying early low-grade appendiceal mucinous neoplasm and appendicitis
by: Dong Bai, et al.
Published: (2023-10-01)

Specific Human ATR and ATM Inhibitors Modulate Single Strand DNA Formation in Leishmania major Exposed to Oxidative Agent
by: Raíssa Bernardes da Silva, et al.
Published: (2022-01-01)

Management and prognostic prediction of appendiceal mucinous adenocarcinoma with peritoneal metastasis: a single center study in China
by: Ruiqing Ma, et al.
Published: (2020-04-01)

Mucinous neoplasms of the appendix - A clinicopathologic study of 21 cases with special insight into current classification & controversies.
by: Rajashree Pradhan, et al.
Published: (2023-01-01)

Incidence of appendiceal neoplasms in appendectomy patients
by: Ricardo E. Núñez-Rocha, et al.
Published: (2023-09-01)

Appendiceal mucinous neoplasm with myxoglobulosis occurring 3 years after perforated barium appendicitis: a case report
by: Takatsugu Fujii, et al.
Published: (2019-07-01)

Organoids From Mucinous Appendiceal Adenocarcinomas as High-Fidelity Models for Individual Therapy
by: Guangyao Liu, et al.
Published: (2022-06-01)

Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
by: Ferney David Gómez-Báez, et al.
Published: (2023-10-01)

<i>atm</i> Mutation and Oxidative Stress Enhance the Pre-Cancerous Effects of UHRF1 Overexpression in Zebrafish Livers
by: Yousra Ajouaou, et al.
Published: (2023-04-01)

Current Status of Treatment among Patients with Appendiceal Tumors—Old Challenges and New Solutions?
by: Katarzyna Chawrylak, et al.
Published: (2024-02-01)

Pseudomyxoma peritonei induced by low-grade appendiceal mucinous neoplasm accompanied by rectal cancer: a case report and literature review
by: Shili Ning, et al.
Published: (2019-04-01)