On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review
Transcatheter aortic valve replacement (TAVR) has become a milestone for the management of aortic stenosis in a growing number of patients who are unfavorable candidates for surgery. With the new generation of transcatheter heart valves (THV), the feasibility of transcatheter mitral valve replacemen...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Prosthesis |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2673-1592/4/1/11 |
| _version_ | 1797443045646401536 |
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| author | Chiara Catalano Salvatore Pasta |
| author_facet | Chiara Catalano Salvatore Pasta |
| author_sort | Chiara Catalano |
| collection | DOAJ |
| description | Transcatheter aortic valve replacement (TAVR) has become a milestone for the management of aortic stenosis in a growing number of patients who are unfavorable candidates for surgery. With the new generation of transcatheter heart valves (THV), the feasibility of transcatheter mitral valve replacement (TMVR) for degenerated mitral bioprostheses and failed annuloplasty rings has been demonstrated. In this setting, computational simulations are modernizing the preoperative planning of transcatheter heart valve interventions by predicting the outcome of the bioprosthesis interaction with the human host in a patient-specific fashion. However, computational modeling needs to carry out increasingly challenging levels including the verification and validation to obtain accurate and realistic predictions. This review aims to provide an overall assessment of the recent advances in computational modeling for TAVR and TMVR as well as gaps in the knowledge limiting model credibility and reliability. |
| first_indexed | 2024-03-09T12:50:27Z |
| format | Article |
| id | doaj.art-e505a0c8fd3646db8c602b506e1d6e24 |
| institution | Directory Open Access Journal |
| issn | 2673-1592 |
| language | English |
| last_indexed | 2024-03-09T12:50:27Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Prosthesis |
| spelling | doaj.art-e505a0c8fd3646db8c602b506e1d6e242023-11-30T22:07:59ZengMDPI AGProsthesis2673-15922022-03-014110211210.3390/prosthesis4010011On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A ReviewChiara Catalano0Salvatore Pasta1Department of Engineering, Università degli Studi di Palermo, Viale delle Scienze, 90128 Palermo, ItalyDepartment of Engineering, Università degli Studi di Palermo, Viale delle Scienze, 90128 Palermo, ItalyTranscatheter aortic valve replacement (TAVR) has become a milestone for the management of aortic stenosis in a growing number of patients who are unfavorable candidates for surgery. With the new generation of transcatheter heart valves (THV), the feasibility of transcatheter mitral valve replacement (TMVR) for degenerated mitral bioprostheses and failed annuloplasty rings has been demonstrated. In this setting, computational simulations are modernizing the preoperative planning of transcatheter heart valve interventions by predicting the outcome of the bioprosthesis interaction with the human host in a patient-specific fashion. However, computational modeling needs to carry out increasingly challenging levels including the verification and validation to obtain accurate and realistic predictions. This review aims to provide an overall assessment of the recent advances in computational modeling for TAVR and TMVR as well as gaps in the knowledge limiting model credibility and reliability.https://www.mdpi.com/2673-1592/4/1/11transcatheter aortic valve replacementin silico modelcomputational fluid dynamicstranscatheter mitral valve replacement |
| spellingShingle | Chiara Catalano Salvatore Pasta On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review Prosthesis transcatheter aortic valve replacement in silico model computational fluid dynamics transcatheter mitral valve replacement |
| title | On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review |
| title_full | On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review |
| title_fullStr | On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review |
| title_full_unstemmed | On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review |
| title_short | On the Modeling of Transcatheter Therapies for the Aortic and Mitral Valves: A Review |
| title_sort | on the modeling of transcatheter therapies for the aortic and mitral valves a review |
| topic | transcatheter aortic valve replacement in silico model computational fluid dynamics transcatheter mitral valve replacement |
| url | https://www.mdpi.com/2673-1592/4/1/11 |
| work_keys_str_mv | AT chiaracatalano onthemodelingoftranscathetertherapiesfortheaorticandmitralvalvesareview AT salvatorepasta onthemodelingoftranscathetertherapiesfortheaorticandmitralvalvesareview |