Primary Small Cell Neuroendocrine Carcinoma of the Endometrium
Background: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. Case Study: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2012-08-01
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| Series: | Case Reports in Oncology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/342006 |
| _version_ | 1818496410367033344 |
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| author | Lisa N. Abaid John S. Cupp John V. Brown III Bram H. Goldstein |
| author_facet | Lisa N. Abaid John S. Cupp John V. Brown III Bram H. Goldstein |
| author_sort | Lisa N. Abaid |
| collection | DOAJ |
| description | Background: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. Case Study: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was negative for CD3 and CD20. Prior to chemotherapy, a completion lymphadenectomy was indicated to determine the presence of nodal metastases. Conclusion: The prognosis of small cell neuroendocrine carcinoma of the endometrium is unfavorable but prompt detection with surgery and adjuvant therapy may confer a better clinical outcome. |
| first_indexed | 2024-12-10T18:33:03Z |
| format | Article |
| id | doaj.art-e5060709821d4883aff9619d6687bac5 |
| institution | Directory Open Access Journal |
| issn | 1662-6575 |
| language | English |
| last_indexed | 2024-12-10T18:33:03Z |
| publishDate | 2012-08-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj.art-e5060709821d4883aff9619d6687bac52022-12-22T01:37:53ZengKarger PublishersCase Reports in Oncology1662-65752012-08-015243944310.1159/000342006342006Primary Small Cell Neuroendocrine Carcinoma of the EndometriumLisa N. AbaidJohn S. CuppJohn V. Brown IIIBram H. GoldsteinBackground: Small cell neuroendocrine carcinoma is very rarely encountered within the endometrium. Case Study: A patient underwent a hysterectomy and salpingo-oophorectomy for a suspicious gynecologic condition. Pathology revealed invasive small cell neuroendocrine carcinoma of the endometrium; the neoplasm exhibited positive immunoreactivity for synaptophysin, pancytokeratin and CD56 but was negative for CD3 and CD20. Prior to chemotherapy, a completion lymphadenectomy was indicated to determine the presence of nodal metastases. Conclusion: The prognosis of small cell neuroendocrine carcinoma of the endometrium is unfavorable but prompt detection with surgery and adjuvant therapy may confer a better clinical outcome.http://www.karger.com/Article/FullText/342006EndometriumGynecologic oncologySmall cell neuroendocrine carcinoma |
| spellingShingle | Lisa N. Abaid John S. Cupp John V. Brown III Bram H. Goldstein Primary Small Cell Neuroendocrine Carcinoma of the Endometrium Case Reports in Oncology Endometrium Gynecologic oncology Small cell neuroendocrine carcinoma |
| title | Primary Small Cell Neuroendocrine Carcinoma of the Endometrium |
| title_full | Primary Small Cell Neuroendocrine Carcinoma of the Endometrium |
| title_fullStr | Primary Small Cell Neuroendocrine Carcinoma of the Endometrium |
| title_full_unstemmed | Primary Small Cell Neuroendocrine Carcinoma of the Endometrium |
| title_short | Primary Small Cell Neuroendocrine Carcinoma of the Endometrium |
| title_sort | primary small cell neuroendocrine carcinoma of the endometrium |
| topic | Endometrium Gynecologic oncology Small cell neuroendocrine carcinoma |
| url | http://www.karger.com/Article/FullText/342006 |
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