Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates
Subepithelial infiltrates secondary to adenoviral keratoconjunctivitis may persist for years and cause blurred vision, halos, glare, and photophobia. These infiltrates arise from immune reaction against the virus, and few studies have reported topical cyclosporine A to be effective in the treatment...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2016-03-01
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| Series: | Case Reports in Ophthalmology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/444784 |
| _version_ | 1811268627839582208 |
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| author | Betül N. Bayraktutar Ömür Ö. Uçakhan |
| author_facet | Betül N. Bayraktutar Ömür Ö. Uçakhan |
| author_sort | Betül N. Bayraktutar |
| collection | DOAJ |
| description | Subepithelial infiltrates secondary to adenoviral keratoconjunctivitis may persist for years and cause blurred vision, halos, glare, and photophobia. These infiltrates arise from immune reaction against the virus, and few studies have reported topical cyclosporine A to be effective in the treatment of subepithelial infiltrates. Herein, we describe a patient with adenoviral keratoconjunctivitis-related subepithelial infiltrates who did not respond to treatment with a new topical cyclosporine A emulsion prepared with castor oil (Depores 0.05%; Deva İlaç, Kocaeli, Turkey), while the FDA-approved nanoemulsion formulation provided improvement in symptoms and reduced the inflammatory reaction (Restasis 0.05%; Allergan, Irvine, Calif., USA). |
| first_indexed | 2024-04-12T21:26:18Z |
| format | Article |
| id | doaj.art-e50aaa70f9584ca5a392b4e51e186903 |
| institution | Directory Open Access Journal |
| issn | 1663-2699 |
| language | English |
| last_indexed | 2024-04-12T21:26:18Z |
| publishDate | 2016-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Ophthalmology |
| spelling | doaj.art-e50aaa70f9584ca5a392b4e51e1869032022-12-22T03:16:10ZengKarger PublishersCase Reports in Ophthalmology1663-26992016-03-017113514010.1159/000444784444784Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial InfiltratesBetül N. BayraktutarÖmür Ö. UçakhanSubepithelial infiltrates secondary to adenoviral keratoconjunctivitis may persist for years and cause blurred vision, halos, glare, and photophobia. These infiltrates arise from immune reaction against the virus, and few studies have reported topical cyclosporine A to be effective in the treatment of subepithelial infiltrates. Herein, we describe a patient with adenoviral keratoconjunctivitis-related subepithelial infiltrates who did not respond to treatment with a new topical cyclosporine A emulsion prepared with castor oil (Depores 0.05%; Deva İlaç, Kocaeli, Turkey), while the FDA-approved nanoemulsion formulation provided improvement in symptoms and reduced the inflammatory reaction (Restasis 0.05%; Allergan, Irvine, Calif., USA).http://www.karger.com/Article/FullText/444784Adenoviral keratoconjunctivitisSubepithelial infiltratesCyclosporine A |
| spellingShingle | Betül N. Bayraktutar Ömür Ö. Uçakhan Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates Case Reports in Ophthalmology Adenoviral keratoconjunctivitis Subepithelial infiltrates Cyclosporine A |
| title | Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates |
| title_full | Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates |
| title_fullStr | Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates |
| title_full_unstemmed | Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates |
| title_short | Comparison of Efficacy of Two Different Topical 0.05% Cyclosporine A Formulations in the Treatment of Adenoviral Keratoconjunctivitis-Related Subepithelial Infiltrates |
| title_sort | comparison of efficacy of two different topical 0 05 cyclosporine a formulations in the treatment of adenoviral keratoconjunctivitis related subepithelial infiltrates |
| topic | Adenoviral keratoconjunctivitis Subepithelial infiltrates Cyclosporine A |
| url | http://www.karger.com/Article/FullText/444784 |
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