Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique
Plectranthus amboinicus (Lour.) Spreng is a medicinal herb with bioactive compounds and known to have pharmacological properties. To obtain the extract of this herb, efficient extraction technique with high extraction rates is needed. Microwave-assisted extraction (MAE) is a green extraction techniq...
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| Format: | Article |
| Language: | English |
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AIDIC Servizi S.r.l.
2019-01-01
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| Series: | Chemical Engineering Transactions |
| Online Access: | https://www.cetjournal.it/index.php/cet/article/view/9600 |
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| author | Nabilah A. Samad Dayang Norulfairuz Abang Zaidel Eraricar Salleh Abdul Halim Mohd Yusof Daniel Joe Dailin Dyg Norkhairunnisa Abang Zaidel |
| author_facet | Nabilah A. Samad Dayang Norulfairuz Abang Zaidel Eraricar Salleh Abdul Halim Mohd Yusof Daniel Joe Dailin Dyg Norkhairunnisa Abang Zaidel |
| author_sort | Nabilah A. Samad |
| collection | DOAJ |
| description | Plectranthus amboinicus (Lour.) Spreng is a medicinal herb with bioactive compounds and known to have pharmacological properties. To obtain the extract of this herb, efficient extraction technique with high extraction rates is needed. Microwave-assisted extraction (MAE) is a green extraction technique with shorter irradiation time, less solvent used and lower CO2 emission compared to other conventional extraction methods. The objective of the study was to determine the optimum operating extraction condition of P. amboinicus using MAE by varying the irradiation time, solvent concentration and solvent-to-solid ratio to obtain optimum yield extract and conducted using response surface methodology (RSM). The extract obtained at optimum condition was characterized for its antioxidant properties. The RSM results show that the optimum condition of P. amboinicus extraction was at 2 min, 30 % ethanol concentration and solvent-to-solid ratio at 30 mL/g with yield extract obtained at 39.81 wt %. The result antioxidants activity of the P. amboinicus extract showed IC50 value of 4.63 mg/mL while the inhibition of DPPH radical scavenging activity from the trolox standard was 5.48 ± 0.77 mg trolox equivalents (TEQ)/g extract. The study proved MAE is a better alternative compared to conventional extraction method with 16.8 % higher yield and the extract of P. amboinicus can be potentially applied in healthcare and pharmaceutical industry. |
| first_indexed | 2024-12-17T07:42:45Z |
| format | Article |
| id | doaj.art-e50aacedfdec4de3a588ea9230d4d762 |
| institution | Directory Open Access Journal |
| issn | 2283-9216 |
| language | English |
| last_indexed | 2024-12-17T07:42:45Z |
| publishDate | 2019-01-01 |
| publisher | AIDIC Servizi S.r.l. |
| record_format | Article |
| series | Chemical Engineering Transactions |
| spelling | doaj.art-e50aacedfdec4de3a588ea9230d4d7622022-12-21T21:58:06ZengAIDIC Servizi S.r.l.Chemical Engineering Transactions2283-92162019-01-017210.3303/CET1972067Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted TechniqueNabilah A. SamadDayang Norulfairuz Abang ZaidelEraricar SallehAbdul Halim Mohd YusofDaniel Joe DailinDyg Norkhairunnisa Abang ZaidelPlectranthus amboinicus (Lour.) Spreng is a medicinal herb with bioactive compounds and known to have pharmacological properties. To obtain the extract of this herb, efficient extraction technique with high extraction rates is needed. Microwave-assisted extraction (MAE) is a green extraction technique with shorter irradiation time, less solvent used and lower CO2 emission compared to other conventional extraction methods. The objective of the study was to determine the optimum operating extraction condition of P. amboinicus using MAE by varying the irradiation time, solvent concentration and solvent-to-solid ratio to obtain optimum yield extract and conducted using response surface methodology (RSM). The extract obtained at optimum condition was characterized for its antioxidant properties. The RSM results show that the optimum condition of P. amboinicus extraction was at 2 min, 30 % ethanol concentration and solvent-to-solid ratio at 30 mL/g with yield extract obtained at 39.81 wt %. The result antioxidants activity of the P. amboinicus extract showed IC50 value of 4.63 mg/mL while the inhibition of DPPH radical scavenging activity from the trolox standard was 5.48 ± 0.77 mg trolox equivalents (TEQ)/g extract. The study proved MAE is a better alternative compared to conventional extraction method with 16.8 % higher yield and the extract of P. amboinicus can be potentially applied in healthcare and pharmaceutical industry.https://www.cetjournal.it/index.php/cet/article/view/9600 |
| spellingShingle | Nabilah A. Samad Dayang Norulfairuz Abang Zaidel Eraricar Salleh Abdul Halim Mohd Yusof Daniel Joe Dailin Dyg Norkhairunnisa Abang Zaidel Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique Chemical Engineering Transactions |
| title | Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique |
| title_full | Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique |
| title_fullStr | Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique |
| title_full_unstemmed | Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique |
| title_short | Optimization of Plectranthus amboinicus (Lour.) Spreng Extraction Process using Microwave-Assisted Technique |
| title_sort | optimization of plectranthus amboinicus lour spreng extraction process using microwave assisted technique |
| url | https://www.cetjournal.it/index.php/cet/article/view/9600 |
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