Chorea, Pruritus and Polycythemia: Looking for Clues
Chorea is a movement disorder usually due to vascular, hereditary, metabolic or drug- induced causes, and has rarely been reported in association with polycythemia vera (PV). Polycythemic chorea is an uncommon clinical entity that occurs more often in elderly women. PV is a treatable cause of chorea...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2019-02-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/1039 |
| _version_ | 1818237728449363968 |
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| author | Vânia Rodrigues Carolina Lopes Adilson Marcolino Madalena Pinto |
| author_facet | Vânia Rodrigues Carolina Lopes Adilson Marcolino Madalena Pinto |
| author_sort | Vânia Rodrigues |
| collection | DOAJ |
| description | Chorea is a movement disorder usually due to vascular, hereditary, metabolic or drug- induced causes, and has rarely been reported in association with polycythemia vera (PV). Polycythemic chorea is an uncommon clinical entity that occurs more often in elderly women. PV is a treatable cause of chorea and must be considered during the diagnostic approach. We report the case of a 75-year-old woman with involuntary movements of the mouth and face with subsequent involvement of the trunk and limbs who was admitted for investigation of the chorea. The patient had the haematological attributes of PV and a positive mutation in the janus kinase 2 (JAK2) gene, and was therefore treated with hydroxyurea which led to a marked reduction in the chorea and improvement in haematological parameters. Various aetiologies of chorea must be considered in the elderly. The present case illustrates the importance of considering PV in the differential diagnosis, since its treatment leads to chorea resolution, thus avoiding serious complications. |
| first_indexed | 2024-12-12T12:30:22Z |
| format | Article |
| id | doaj.art-e50aba8c1bda478bbba9a9e04f48b80e |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-12-12T12:30:22Z |
| publishDate | 2019-02-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-e50aba8c1bda478bbba9a9e04f48b80e2022-12-22T00:24:26ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942019-02-0110.12890/2019_0010391039Chorea, Pruritus and Polycythemia: Looking for CluesVânia Rodrigues0Carolina Lopes1Adilson Marcolino2Madalena Pinto3Internal Medicine Department, Centro Hospitalar de Leiria, Leiria, PortugalNeurology Department, Centro Hospitalar de São João, Porto, PortugalNeurology Department, Centro Hospitalar de São João, Porto, PortugalNeurology Department, Centro Hospitalar de São João, Porto, PortugalChorea is a movement disorder usually due to vascular, hereditary, metabolic or drug- induced causes, and has rarely been reported in association with polycythemia vera (PV). Polycythemic chorea is an uncommon clinical entity that occurs more often in elderly women. PV is a treatable cause of chorea and must be considered during the diagnostic approach. We report the case of a 75-year-old woman with involuntary movements of the mouth and face with subsequent involvement of the trunk and limbs who was admitted for investigation of the chorea. The patient had the haematological attributes of PV and a positive mutation in the janus kinase 2 (JAK2) gene, and was therefore treated with hydroxyurea which led to a marked reduction in the chorea and improvement in haematological parameters. Various aetiologies of chorea must be considered in the elderly. The present case illustrates the importance of considering PV in the differential diagnosis, since its treatment leads to chorea resolution, thus avoiding serious complications.https://www.ejcrim.com/index.php/EJCRIM/article/view/1039Choreapolycythemia veraelderly |
| spellingShingle | Vânia Rodrigues Carolina Lopes Adilson Marcolino Madalena Pinto Chorea, Pruritus and Polycythemia: Looking for Clues European Journal of Case Reports in Internal Medicine Chorea polycythemia vera elderly |
| title | Chorea, Pruritus and Polycythemia: Looking for Clues |
| title_full | Chorea, Pruritus and Polycythemia: Looking for Clues |
| title_fullStr | Chorea, Pruritus and Polycythemia: Looking for Clues |
| title_full_unstemmed | Chorea, Pruritus and Polycythemia: Looking for Clues |
| title_short | Chorea, Pruritus and Polycythemia: Looking for Clues |
| title_sort | chorea pruritus and polycythemia looking for clues |
| topic | Chorea polycythemia vera elderly |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/1039 |
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