Agrimol B alleviates cisplatin-induced acute kidney injury by activating the Sirt1/Nrf2 signaling pathway in mice

Agrimol B alleviates cisplatin-induced acute kidney injury by activating the Sirt1/Nrf2 signaling pathway in mice

Cisplatin (CDDP) is a widely used chemotherapeutic agent that has remarkable antineoplastic effects. However, CDDP can cause severe acute kidney injury (AKI), which limits its clinical application. Agrimol B is the main active ingredient found in Agrimonia pilosa Ledeb and has a variety of pharmacol...

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Bibliographic Details
Main Authors: Tang Jiarui, Li Longhui, Chen Zhijian, Liao Cuiting, Hu Kai, Yang Yongqiang, Huang Jiayi, Tang Li, Zhang Li, Li Longjiang
Format: Article
Language:English
Published: China Science Publishing & Media Ltd. 2024-02-01
Series:Acta Biochimica et Biophysica Sinica
Subjects:
cisplatin
acute kidney injury
agrimol B
Sirt1
oxidative stress
Online Access:https://www.sciengine.com/doi/10.3724/abbs.2023285

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