Detection of mild cognitive impairment based on mouse movement data of trail making test

Mild cognitive impairment (MCI) has 10%–20% prevalence in the population above the age of 65, and a significant portion of these people will go on to develop dementia later in their lives. However, if MCI is detected early, preventative measures can be taken to delay the onset of severe symptoms. Cu...

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Main Authors: Gergely Hanczár, Erika Griechisch, Nóra Ovád, Olivér Máté Törteli, Gábor Tóth, Dávid Hanák, Balázs Vértes, András Horváth, Anita Kamondi
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Informatics in Medicine Unlocked
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S235291482200257X
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author Gergely Hanczár
Erika Griechisch
Nóra Ovád
Olivér Máté Törteli
Gábor Tóth
Dávid Hanák
Balázs Vértes
András Horváth
Anita Kamondi
author_facet Gergely Hanczár
Erika Griechisch
Nóra Ovád
Olivér Máté Törteli
Gábor Tóth
Dávid Hanák
Balázs Vértes
András Horváth
Anita Kamondi
author_sort Gergely Hanczár
collection DOAJ
description Mild cognitive impairment (MCI) has 10%–20% prevalence in the population above the age of 65, and a significant portion of these people will go on to develop dementia later in their lives. However, if MCI is detected early, preventative measures can be taken to delay the onset of severe symptoms. Current diagnostic methods for MCI are not suitable for regular wide-scale screening. Advances in machine learning algorithms in combination with digital movement data offer rich possibilities for automated MCI detection. This paper introduces a machine learning model that effectively predicts MCI based on only a few seconds of computer mouse movement. To our knowledge, studies directly comparable to ours have not been done before. On a dataset of 70 participants, we demonstrated 80% accuracy in distinguishing healthy controls from patients with MCI. This gives an opportunity to develop a cost-efficient and easy-to-use screening method that could aid the work of healthcare professionals.
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spelling doaj.art-e50d901db9f949f2a615166ca4fa712d2022-12-22T04:21:49ZengElsevierInformatics in Medicine Unlocked2352-91482022-01-0135101120Detection of mild cognitive impairment based on mouse movement data of trail making testGergely Hanczár0Erika Griechisch1Nóra Ovád2Olivér Máté Törteli3Gábor Tóth4Dávid Hanák5Balázs Vértes6András Horváth7Anita Kamondi8Cursor Insight Ltd., 20-22 Wenlock Road, N1 7GU, London, United Kingdom; Patient Record, 20-22 Wenlock Road, N1 7GU, London, United KingdomCursor Insight Ltd., 20-22 Wenlock Road, N1 7GU, London, United Kingdom; Patient Record, 20-22 Wenlock Road, N1 7GU, London, United KingdomCursor Insight Ltd., 20-22 Wenlock Road, N1 7GU, London, United KingdomCursor Insight Ltd., 20-22 Wenlock Road, N1 7GU, London, United KingdomPatient Record, 20-22 Wenlock Road, N1 7GU, London, United KingdomCursor Insight Ltd., 20-22 Wenlock Road, N1 7GU, London, United Kingdom; Correspondence to: Mester utca 1 3/18, Budapest, H-1095, Hungary.Precognize, Németvölgyi út 2, 1126, Budapest, HungaryNational Institute of Mental Health, Neurology and Neurosurgery, Amerikai út 57, 1145, Budapest, Hungary; Semmelweis University, Department of Anatomy, Histology and Embryology, Tűzoltó u. 58, 1094, Budapest, HungaryNational Institute of Mental Health, Neurology and Neurosurgery, Amerikai út 57, 1145, Budapest, Hungary; Semmelweis University, Department of Neurology, Balassa u. 6, 1083, Budapest, HungaryMild cognitive impairment (MCI) has 10%–20% prevalence in the population above the age of 65, and a significant portion of these people will go on to develop dementia later in their lives. However, if MCI is detected early, preventative measures can be taken to delay the onset of severe symptoms. Current diagnostic methods for MCI are not suitable for regular wide-scale screening. Advances in machine learning algorithms in combination with digital movement data offer rich possibilities for automated MCI detection. This paper introduces a machine learning model that effectively predicts MCI based on only a few seconds of computer mouse movement. To our knowledge, studies directly comparable to ours have not been done before. On a dataset of 70 participants, we demonstrated 80% accuracy in distinguishing healthy controls from patients with MCI. This gives an opportunity to develop a cost-efficient and easy-to-use screening method that could aid the work of healthcare professionals.http://www.sciencedirect.com/science/article/pii/S235291482200257XMouse movementMild cognitive impairmentEarly detectionMachine learning
spellingShingle Gergely Hanczár
Erika Griechisch
Nóra Ovád
Olivér Máté Törteli
Gábor Tóth
Dávid Hanák
Balázs Vértes
András Horváth
Anita Kamondi
Detection of mild cognitive impairment based on mouse movement data of trail making test
Informatics in Medicine Unlocked
Mouse movement
Mild cognitive impairment
Early detection
Machine learning
title Detection of mild cognitive impairment based on mouse movement data of trail making test
title_full Detection of mild cognitive impairment based on mouse movement data of trail making test
title_fullStr Detection of mild cognitive impairment based on mouse movement data of trail making test
title_full_unstemmed Detection of mild cognitive impairment based on mouse movement data of trail making test
title_short Detection of mild cognitive impairment based on mouse movement data of trail making test
title_sort detection of mild cognitive impairment based on mouse movement data of trail making test
topic Mouse movement
Mild cognitive impairment
Early detection
Machine learning
url http://www.sciencedirect.com/science/article/pii/S235291482200257X
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