Significance of α-Myosin Heavy Chain (<i>MYH6</i>) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases

Significance of α-Myosin Heavy Chain (<i>MYH6</i>) Variants in Hypoplastic Left Heart Syndrome and Related Cardiovascular Diseases

Hypoplastic left heart syndrome (HLHS) is a severe congenital heart disease (CHD) with complex genetic inheritance. HLHS segregates with other left ventricular outflow tract (LVOT) malformations in families, and can present as either an isolated phenotype or as a feature of a larger genetic disorder...

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Hlavní autoři: Melissa Anfinson, Robert H. Fitts, John W. Lough, Jeanne M. James, Pippa M. Simpson, Stephanie S. Handler, Michael E. Mitchell, Aoy Tomita-Mitchell
Médium: Článek
Jazyk:English
Vydáno: MDPI AG 2022-05-01
Edice:Journal of Cardiovascular Development and Disease
Témata:
hypoplastic left heart syndrome
cardiac myosin heavy chain
congenital heart disease
rare variant analysis
On-line přístup:https://www.mdpi.com/2308-3425/9/5/144

Internet

https://www.mdpi.com/2308-3425/9/5/144

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