CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs

Abstract Genome editing using programmable nucleases has revolutionized biomedical research. CRISPR-Cas9 mediated zygote genome editing enables high efficient production of knockout animals suitable for studying development and relevant human diseases. Here we report efficient disabling pancreatogen...

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Bibliographic Details
Main Authors: Jun Wu, Marcela Vilarino, Keiichiro Suzuki, Daiji Okamura, Yanina Soledad Bogliotti, Insung Park, Joan Rowe, Bret McNabb, Pablo Juan Ross, Juan Carlos Izpisua Belmonte
Format: Article
Language:English
Published: Nature Portfolio 2017-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08596-5

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