Moderate restriction of macrophage-tropic human immunodeficiency virus type 1 by SAMHD1 in monocyte-derived macrophages.

Moderate restriction of macrophage-tropic human immunodeficiency virus type 1 by SAMHD1 in monocyte-derived macrophages.

Macrophage-tropic human immunodeficiency virus type 1 (HIV-1) strains are able to grow to high titers in human monocyte-derived macrophages. However, it was recently reported that cellular protein SAMHD1 restricts HIV-1 replication in human cells of the myeloid lineage, including monocyte-derived ma...

Full description

Bibliographic Details
Main Authors:	Kahoru Taya, Emi E Nakayama, Tatsuo Shioda
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2014-01-01
Series:	PLoS ONE
Online Access:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090969&type=printable

Similar Items

Investigating SAMHD1 restriction of HIV-1 in stem cell-derived macrophages
by: Warner, D
Published: (2020)

Intrinsic resistance of HIV-1 to SAMHD1 restriction permits efficient macrophage infection
by: T. Plitnik, et al.
Published: (2017-12-01)

Host SAMHD1 protein restricts endogenous reverse transcription of HIV-1 in nondividing macrophages
by: Bijan Mahboubi, et al.
Published: (2018-10-01)

A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages
by: Mlcochova, P, et al.
Published: (2017)

Gene editing of SAMHD1 in macrophage-like cells reveals complex relationships between SAMHD1 phospho-regulation, HIV-1 restriction, and cellular dNTP levels
by: Moritz Schüssler, et al.
Published: (2023-10-01)

Incomplete Suppression of HIV-1 by SAMHD1 Permits Efficient Macrophage Infection
by: Timothy Plitnik, et al.
Published: (2018-12-01)

Interferon-Stimulated SAMHD1 Restricts Hepatitis C Virus Replication
by: Ni An, et al.
Published: (2020-06-01)

Electrostatic potential of human immunodeficiency virus type 2 and rhesus macaque simian immunodeficiency virus capsid proteins
by: Katarzyna eBozek, et al.
Published: (2012-06-01)

Generation of macrophages with altered viral sensitivity from genome-edited rhesus macaque iPSCs to model human disease
by: Yoshihiro Iwamoto, et al.
Published: (2021-06-01)

A single amino acid substitution of the human immunodeficiency virus type 1 capsid protein affects viral sensitivity to TRIM5α
by: Shioda Tatsuo, et al.
Published: (2010-07-01)

Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction
by: Kono Ken, et al.
Published: (2010-09-01)

Increased expression and phosphorylation of SAMHD1 in SIV and HIV encephalitis is associated with proliferation of brain macrophages
by: A.A. Lindgren, et al.
Published: (2017-12-01)

Host factor SAMHD1 restricts DNA viruses in non-dividing myeloid cells.
by: Joseph A Hollenbaugh, et al.
Published: (2013-01-01)

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac
by: Brandariz-Nuñez Alberto, et al.
Published: (2012-06-01)

Hepcidin Induces M1 Macrophage Polarization in Monocytes or THP-1 Derived Macrophages
by: Enna Liu, et al.
Published: (2019-09-01)

SAMHD1: a new insight into HIV-1 restriction in myeloid cells
by: Wu Li, et al.
Published: (2011-07-01)

Modification of a loop sequence between α-helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV-1) derivative that has simian immunodeficiency virus (SIVmac239) <it>vif </it>and CA α-helices 4 and 5 loop improves replication in cynomolgus monkey cells
by: Adachi Akio, et al.
Published: (2009-08-01)

Phospho-dependent Regulation of SAMHD1 Oligomerisation Couples Catalysis and Restriction.
by: Laurence H Arnold, et al.
Published: (2015-10-01)

IL‐21 regulates macrophage activation in human monocytic THP‐1‐derived macrophages
by: Leilei Jian, et al.
Published: (2021-09-01)

Attenuation of reverse transcriptase facilitates SAMHD1 restriction of HIV-1 in cycling cells
by: Ming-Han C. Tsai, et al.
Published: (2023-05-01)

Interferon-alpha mediates restriction of human immunodeficiency virus type-1 replication in primary human macrophages at an early stage of replication.
by: Kelly M Cheney, et al.
Published: (2010-10-01)

TLR4-Mediated Pathway Triggers Interferon-Independent G0 Arrest and Antiviral SAMHD1 Activity in Macrophages
by: Petra Mlcochova, et al.
Published: (2020-03-01)

Substrates and Inhibitors of SAMHD1.
by: Joseph A Hollenbaugh, et al.
Published: (2017-01-01)

SAMHD1 restricts HIV-1 replication and regulates interferon production in mouse myeloid cells.
by: Ruonan Zhang, et al.
Published: (2014-01-01)

The SAMHD1-MX2 axis restricts HIV-1 infection at postviral DNA synthesis
by: Haoran Guo, et al.
Published: (2024-07-01)

Cell-to-Cell Spreading of HIV-1 in Myeloid Target Cells Escapes SAMHD1 Restriction
by: Maorong Xie, et al.
Published: (2019-12-01)

SUMOylation of SAMHD1 at Lysine 595 is required for HIV-1 restriction in non-cycling cells
by: Charlotte Martinat, et al.
Published: (2021-07-01)

PP 1.42 – 00114 Functional Polarization of Human Monocyte-Derived Macrophage into M1-Proinflammatory Cells Restricts Both HIV-1 and Zika Virus Replication
by: G. Poli, et al.
Published: (2022-12-01)

Impact of Superparamagnetic Iron Oxide Nanoparticles on THP-1 Monocytes and Monocyte-Derived Macrophages
by: Christina Polasky, et al.
Published: (2022-02-01)

Construction of Human Monocyte Derived Macrophages Armed with Oncolytic Viruses
by: Munitta Muthana, et al.
Published: (2013-07-01)

SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity
by: Christopher H. Mauney, et al.
Published: (2018-04-01)

Interferon-inducible SAMHD1 restricts viral replication through downregulation of lipid synthesis
by: Ni An, et al.
Published: (2022-11-01)

Host hindrance to HIV-1 replication in monocytes and macrophages
by: Pancino Gianfranco, et al.
Published: (2010-04-01)

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4<sup>+</sup> T-cells
by: Descours Benjamin, et al.
Published: (2012-10-01)

Characterisation of SAMHD1's ancestral function
by: Davenne, T
Published: (2018)

SAMHD1 … and Viral Ways around It
by: Janina Deutschmann, et al.
Published: (2021-03-01)

SAMHD1 Functions and Human Diseases
by: Si’Ana A. Coggins, et al.
Published: (2020-03-01)

Moderate Increase of Indoxyl Sulfate Promotes Monocyte Transition into Profibrotic Macrophages.
by: Chiara Barisione, et al.
Published: (2016-01-01)

Rabies virus uniquely reprograms the transcriptome of human monocyte-derived macrophages
by: Carmen W.E. Embregts, et al.
Published: (2023-01-01)

PIM kinases facilitate lentiviral evasion from SAMHD1 restriction via Vpx phosphorylation
by: Kei Miyakawa, et al.
Published: (2019-04-01)