<i>O</i>-GlcNAcylation Links Nutrition to the Epigenetic Downregulation of <i>UNC5A</i> during Colon Carcinogenesis

<i>O</i>-GlcNAcylation Links Nutrition to the Epigenetic Downregulation of <i>UNC5A</i> during Colon Carcinogenesis

While it is now accepted that nutrition can influence the epigenetic modifications occurring in colorectal cancer (CRC), the underlying mechanisms are not fully understood. Among the tumor suppressor genes frequently epigenetically downregulated in CRC, the four related genes of the <i>UNC5<...

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Bibliographic Details
Main Authors: Amélie Decourcelle, Ninon Very, Madjid Djouina, Ingrid Loison, Julien Thévenet, Mathilde Body-Malapel, Eric Lelièvre, Olivier Coqueret, Dominique Leprince, Ikram El Yazidi-Belkoura, Vanessa Dehennaut
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Cancers
Subjects:
UNC5A
<i>O</i>-GlcNAcylation
OGT
EZH2
nutrition
epigenetics
Online Access:https://www.mdpi.com/2072-6694/12/11/3168

Internet

https://www.mdpi.com/2072-6694/12/11/3168

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