Keratin 17 Promotes T Cell Response in Allergic Contact Dermatitis by Upregulating C–C Motif Chemokine Ligand 20

Keratin 17 Promotes T Cell Response in Allergic Contact Dermatitis by Upregulating C–C Motif Chemokine Ligand 20

Allergic contact dermatitis (ACD) is a delayed-type hypersensitivity response to skin contact allergens in which keratinocytes are critical in the initiation of early responses. Keratin 17 (K17) is a cytoskeletal protein inducible under stressful conditions and regulates multiple cellular processes,...

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Bibliographic Details
Main Authors: Yixin Luo, Zhenlai Zhu, Bing Li, Xiaocui Bai, Hui Fang, Pei Qiao, Jiaoling Chen, Chen Zhang, Dalong Zhi, Erle Dang, Gang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Immunology
Subjects:
allergic contact dermatitis
contact hypersensitivity
keratinocytes
keratin 17
CCL20
T cell infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.764793/full

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