Cognitive remediation in schizophrenia: What happens after 10 years?
Cognitive Remediation Therapy (CRT) represents the gold standard treatment for cognitive impairment in schizophrenia, but the permanence of its effects over time have been poorly investigated. Our study aims to evaluate long lasting cognitive and functional effects of CRT together with standard reha...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Schizophrenia Research: Cognition |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2215001322000166 |
| _version_ | 1818470309939904512 |
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| author | Mariachiara Buonocore Marco Spangaro Margherita Bechi Stefania Trezzani Rachele Terragni Francesca Martini Giulia Agostoni Federica Cocchi Federica Cuoco Carmelo Guglielmino Marta Bosia Roberto Cavallaro |
| author_facet | Mariachiara Buonocore Marco Spangaro Margherita Bechi Stefania Trezzani Rachele Terragni Francesca Martini Giulia Agostoni Federica Cocchi Federica Cuoco Carmelo Guglielmino Marta Bosia Roberto Cavallaro |
| author_sort | Mariachiara Buonocore |
| collection | DOAJ |
| description | Cognitive Remediation Therapy (CRT) represents the gold standard treatment for cognitive impairment in schizophrenia, but the permanence of its effects over time have been poorly investigated. Our study aims to evaluate long lasting cognitive and functional effects of CRT together with standard rehabilitation interventions (SRT) in a group of patients diagnosed with schizophrenia, 10 years after the end of the treatment. Forty patients, previously included in a 5-year follow-up study evaluating the effects of CRT combined with SRT, were revalued 10 years after the complete of the intervention. Results revealed that cognitive and functional improvements of combined CRT/SRT interventions are still preserved 10 years after the end of the treatments, with the only exception of psychomotor speed and coordination cognitive subdomain. Moreover, investigating persistence of the influence of SRT, patients that underwent a shorter SRT following CRT (six months vs one year) showed worsened processing speed abilities.This is the first study confirming that cognitive and functional improvements of joint CRT/SRT interventions are still conserved 10 years after the end of the treatments. Preliminary datas suggest that a longer SRT following CRT may lead to significant benefits, in terms of cognitive gains, in patients affected by schizophrenia. |
| first_indexed | 2024-04-13T21:35:41Z |
| format | Article |
| id | doaj.art-e51d8ac4f33f413d945674432c36b232 |
| institution | Directory Open Access Journal |
| issn | 2215-0013 |
| language | English |
| last_indexed | 2024-04-13T21:35:41Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Schizophrenia Research: Cognition |
| spelling | doaj.art-e51d8ac4f33f413d945674432c36b2322022-12-22T02:29:00ZengElsevierSchizophrenia Research: Cognition2215-00132022-09-0129100251Cognitive remediation in schizophrenia: What happens after 10 years?Mariachiara Buonocore0Marco Spangaro1Margherita Bechi2Stefania Trezzani3Rachele Terragni4Francesca Martini5Giulia Agostoni6Federica Cocchi7Federica Cuoco8Carmelo Guglielmino9Marta Bosia10Roberto Cavallaro11Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy; Corresponding author at: San Raffaele Scientific Institute and Hospital, Department of Clinical Neurosciences, Via Stamira d'Ancona 20, 20127 Milano, Italy.Department of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyVita-Salute San Raffaele University, Milan, ItalyVita-Salute San Raffaele University, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyVita-Salute San Raffaele University, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, Italy; Vita-Salute San Raffaele University, Milan, ItalyDepartment of Clinical Neurosciences, IRCCS San Raffaele Scientific Institute, Milan, ItalyCognitive Remediation Therapy (CRT) represents the gold standard treatment for cognitive impairment in schizophrenia, but the permanence of its effects over time have been poorly investigated. Our study aims to evaluate long lasting cognitive and functional effects of CRT together with standard rehabilitation interventions (SRT) in a group of patients diagnosed with schizophrenia, 10 years after the end of the treatment. Forty patients, previously included in a 5-year follow-up study evaluating the effects of CRT combined with SRT, were revalued 10 years after the complete of the intervention. Results revealed that cognitive and functional improvements of combined CRT/SRT interventions are still preserved 10 years after the end of the treatments, with the only exception of psychomotor speed and coordination cognitive subdomain. Moreover, investigating persistence of the influence of SRT, patients that underwent a shorter SRT following CRT (six months vs one year) showed worsened processing speed abilities.This is the first study confirming that cognitive and functional improvements of joint CRT/SRT interventions are still conserved 10 years after the end of the treatments. Preliminary datas suggest that a longer SRT following CRT may lead to significant benefits, in terms of cognitive gains, in patients affected by schizophrenia.http://www.sciencedirect.com/science/article/pii/S2215001322000166SchizophreniaFollow-upQuality of lifeNeurocognitionRehabilitationDaily functioning |
| spellingShingle | Mariachiara Buonocore Marco Spangaro Margherita Bechi Stefania Trezzani Rachele Terragni Francesca Martini Giulia Agostoni Federica Cocchi Federica Cuoco Carmelo Guglielmino Marta Bosia Roberto Cavallaro Cognitive remediation in schizophrenia: What happens after 10 years? Schizophrenia Research: Cognition Schizophrenia Follow-up Quality of life Neurocognition Rehabilitation Daily functioning |
| title | Cognitive remediation in schizophrenia: What happens after 10 years? |
| title_full | Cognitive remediation in schizophrenia: What happens after 10 years? |
| title_fullStr | Cognitive remediation in schizophrenia: What happens after 10 years? |
| title_full_unstemmed | Cognitive remediation in schizophrenia: What happens after 10 years? |
| title_short | Cognitive remediation in schizophrenia: What happens after 10 years? |
| title_sort | cognitive remediation in schizophrenia what happens after 10 years |
| topic | Schizophrenia Follow-up Quality of life Neurocognition Rehabilitation Daily functioning |
| url | http://www.sciencedirect.com/science/article/pii/S2215001322000166 |
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