PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY
Diffuse large B-cell lymphoma with primary involvement of mediastinal lymph nodes is a separate nosological entity that should be distinguished from primary mediastinal large B-cell lymphoma. In most cases, DLBCL with primary involvement of the mediastinum has a poor prognosis. International Prognos...
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| Format: | Article |
| Language: | English |
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University in Nis, Faculty of Medicine
2014-06-01
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| Series: | Acta Medica Medianae |
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| Online Access: | http://publisher.medfak.ni.ac.rs/2014-html/2-broj/Olivera%20Simonovic-Prognostic%20significance.pdf |
| _version_ | 1818888581040570368 |
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| author | Olivera Simonović |
| author_facet | Olivera Simonović |
| author_sort | Olivera Simonović |
| collection | DOAJ |
| description | Diffuse large B-cell lymphoma with primary involvement of mediastinal lymph nodes is a separate nosological entity that should be distinguished from primary mediastinal large B-cell lymphoma. In most cases, DLBCL with primary involvement of the mediastinum has a poor prognosis. International Prognostic Index IPI (age, Ann Arbor clinical stage, Eastern Cooperative Oncology Group (ECOG) performance status, serum LDH, extranodal involvement) and new R-IPI classify patients with DLBCL in certain risk groups and affect the choice of treatment. Clinical stage II in case of patients with DLBCL does not stand for negative prognostic factor. However, the presence of bulky disease in these patients may affect subsequent treatment. Patients with the same IPI risk may have a different response to the applied therapy. For that reason, today, the clinical IPI score must be considered along with biological factors or FDG-PET scan findings. |
| first_indexed | 2024-12-19T16:55:24Z |
| format | Article |
| id | doaj.art-e51fea77a4d74f4c900e59ebb5d64d04 |
| institution | Directory Open Access Journal |
| issn | 0365-4478 1821-2794 |
| language | English |
| last_indexed | 2024-12-19T16:55:24Z |
| publishDate | 2014-06-01 |
| publisher | University in Nis, Faculty of Medicine |
| record_format | Article |
| series | Acta Medica Medianae |
| spelling | doaj.art-e51fea77a4d74f4c900e59ebb5d64d042022-12-21T20:13:26ZengUniversity in Nis, Faculty of MedicineActa Medica Medianae0365-44781821-27942014-06-01532495310.5633/amm.2014.0208 PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDYOlivera Simonović0Clinic for Hematology and Clinical Immunology, Clinical Center Niš, Niš, SerbiaDiffuse large B-cell lymphoma with primary involvement of mediastinal lymph nodes is a separate nosological entity that should be distinguished from primary mediastinal large B-cell lymphoma. In most cases, DLBCL with primary involvement of the mediastinum has a poor prognosis. International Prognostic Index IPI (age, Ann Arbor clinical stage, Eastern Cooperative Oncology Group (ECOG) performance status, serum LDH, extranodal involvement) and new R-IPI classify patients with DLBCL in certain risk groups and affect the choice of treatment. Clinical stage II in case of patients with DLBCL does not stand for negative prognostic factor. However, the presence of bulky disease in these patients may affect subsequent treatment. Patients with the same IPI risk may have a different response to the applied therapy. For that reason, today, the clinical IPI score must be considered along with biological factors or FDG-PET scan findings.http://publisher.medfak.ni.ac.rs/2014-html/2-broj/Olivera%20Simonovic-Prognostic%20significance.pdfmediastinal massprognostic significancediffuse large B-cell lymphoma CS II |
| spellingShingle | Olivera Simonović PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY Acta Medica Medianae mediastinal mass prognostic significance diffuse large B-cell lymphoma CS II |
| title | PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY |
| title_full | PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY |
| title_fullStr | PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY |
| title_full_unstemmed | PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY |
| title_short | PROGNOSTIC SIGNIFICANCE OF MEDIASTINAL MASS IN PATIENTS WITH DIFFUSE LARGE B-CELL LYMPHOMA CS II – CASE STUDY |
| title_sort | prognostic significance of mediastinal mass in patients with diffuse large b cell lymphoma cs ii case study |
| topic | mediastinal mass prognostic significance diffuse large B-cell lymphoma CS II |
| url | http://publisher.medfak.ni.ac.rs/2014-html/2-broj/Olivera%20Simonovic-Prognostic%20significance.pdf |
| work_keys_str_mv | AT oliverasimonovic prognosticsignificanceofmediastinalmassinpatientswithdiffuselargebcelllymphomacsiicasestudy |