Polymorphisms in ERCC1, GSTs, TS and MTHFR predict clinical outcomes of gastric cancer patients treated with platinum/5-Fu-based chemotherapy: a systematic review

Polymorphisms in ERCC1, GSTs, TS and MTHFR predict clinical outcomes of gastric cancer patients treated with platinum/5-Fu-based chemotherapy: a systematic review

<p>Abstract</p> <p>Background</p> <p>Despite genetic polymorphism in response to platinum/5-Fu chemotherapy in gastric cancer (GC) has been studied, data reported so far are conflicting and critical consideration is needed before translation to the treatment of GC.</...

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Bibliographic Details
Main Authors: Wang Zhen, Chen Jun-qiang, Liu Jin-lu, Qin Xin-gan, Huang Yuan
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Gastroenterology
Subjects:
Gastric cancer
Genetic polymorphism
Chemotherapy
Meta-analysis
Online Access:http://www.biomedcentral.com/1471-230X/12/137

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