Upregulation of Serum Sphingosine (d18:1)-1-P Potentially Contributes to Distinguish HCC Including AFP-Negative HCC From Cirrhosis

Upregulation of Serum Sphingosine (d18:1)-1-P Potentially Contributes to Distinguish HCC Including AFP-Negative HCC From Cirrhosis

BackgroundSerum sphingolipids are widely involved in the development of hepatocellular carcinoma (HCC). We investigated the serum sphingolipid profile in patients with HCC or cirrhosis and explored the potential diagnostic efficiency of serum sphingolipid metabolites which may be helpful in differen...

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Bibliographic Details
Main Authors: Yingying Jiang, Cai Tie, Yang Wang, Dandan Bian, Mei Liu, Ting Wang, Yan Ren, Shuang Liu, Li Bai, Yu Chen, Zhongping Duan, Sujun Zheng, Jinlan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
hepatocellular carcinoma
cirrhosis
AFP
sphingolipid
serum
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.01759/full

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