The Aedes aegypti peritrophic matrix controls arbovirus vector competence through HPx1, a heme-induced peroxidase.

The Aedes aegypti peritrophic matrix controls arbovirus vector competence through HPx1, a heme-induced peroxidase.

Aedes aegypti mosquitoes are the main vectors of arboviruses. The peritrophic matrix (PM) is an extracellular layer that surrounds the blood bolus. It acts as an immune barrier that prevents direct contact of bacteria with midgut epithelial cells during blood digestion. Here, we describe a heme-depe...

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Bibliographic Details
Main Authors: Octavio A C Talyuli, Jose Henrique M Oliveira, Vanessa Bottino-Rojas, Gilbert O Silveira, Patricia H Alvarenga, Ana Beatriz F Barletta, Asher M Kantor, Gabriela O Paiva-Silva, Carolina Barillas-Mury, Pedro L Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011149

Internet

https://doi.org/10.1371/journal.ppat.1011149

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