The chemokine receptor CXCR4 regulates satellite cell activation, early expansion, and self-renewal, in response to skeletal muscle injury

The chemokine receptor CXCR4 regulates satellite cell activation, early expansion, and self-renewal, in response to skeletal muscle injury

Acute skeletal muscle injury is followed by satellite cell activation, proliferation, and differentiation to replace damaged fibers with newly regenerated muscle fibers, processes that involve satellite cell interactions with various niche signals. Here we show that satellite cell specific deletion...

Full description

Bibliographic Details
Main Authors: Ahmed S. Shams, Robert W. Arpke, Micah D. Gearhart, Johannes Weiblen, Ben Mai, David Oyler, Darko Bosnakovski, Omayma M. Mahmoud, Gamal M. Hassan, Michael Kyba
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
satellite cells
skeletal muscle
activation
regeneration
CXCR4
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2022.949532/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2022.949532/full

Similar Items