UMAP Based Anomaly Detection for Minimal Residual Disease Quantification within Acute Myeloid Leukemia

UMAP Based Anomaly Detection for Minimal Residual Disease Quantification within Acute Myeloid Leukemia

Leukemia is the most frequent malignancy in children and adolescents, with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) as the most common subtypes. Minimal residual disease (MRD) measured by flow cytometry (FCM) has proven to be a strong prognostic factor in ALL as well as in...

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Bibliographic Details
Main Authors: Lisa Weijler, Florian Kowarsch, Matthias Wödlinger, Michael Reiter, Margarita Maurer-Granofszky, Angela Schumich, Michael N. Dworzak
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
acute myeloid leukemia
anomaly detection
UMAP
set-transformer
self-attention
flow cytometry
Online Access:https://www.mdpi.com/2072-6694/14/4/898

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