Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes
Most yeasts causing infections in humans are part of commensal microflora and etiological agents of different infections when hosts become susceptible, usually due to becoming immunocompromised. The colonization of potentially pathogenic microbes in the oral cavity is increased by poor oral hygiene....
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-03-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/8/3/310 |
| _version_ | 1797446526034771968 |
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| author | Ming-Gene Tu Chih-Chao Lin Ya-Ting Chiang Zi-Li Zhou Li-Yun Hsieh Kai-Ting Chen Yin-Zhi Chen Wen-Chi Cheng Hsiu-Jung Lo |
| author_facet | Ming-Gene Tu Chih-Chao Lin Ya-Ting Chiang Zi-Li Zhou Li-Yun Hsieh Kai-Ting Chen Yin-Zhi Chen Wen-Chi Cheng Hsiu-Jung Lo |
| author_sort | Ming-Gene Tu |
| collection | DOAJ |
| description | Most yeasts causing infections in humans are part of commensal microflora and etiological agents of different infections when hosts become susceptible, usually due to becoming immunocompromised. The colonization of potentially pathogenic microbes in the oral cavity is increased by poor oral hygiene. This follow-up survey was conducted approximately two months after providing information on proper oral care at 10 nursing homes in Taiwan. Among the 117 of 165 residents colonized by yeasts, 67 were colonized by more than one yeast species. A total of 231 isolates comprising eight fungal genera and 25 species were identified. <i>Candida albicans</i> (44.6%) was the dominant species, followed by <i>Candida glabrata</i> (17.7%), <i>Candida parapsilosis</i> (8.7%), <i>Candida tropicalis</i> (7.8%), and <i>Candida pararugosa</i> (7.3%). Residents having a yeast colony-forming unit >10 (OR, 8.897; 95% CI 2.972–26.634; <i>p</i> < 0.001) or using a wheelchair (OR, 4.682; 95% CI 1.599–13.705; <i>p</i> = 0.005) were more likely to be colonized by multiple species. By comparing before and after oral-care education, dry mouth (OR, 3.199; 95% CI 1.448–7.068; <i>p</i> = 0.011) and having heart disease (OR, 2.681; 95% CI 1.068–6.732; <i>p</i> = 0.036) emerged as two independent risk factors for increased density of colonizing yeast. |
| first_indexed | 2024-03-09T13:41:49Z |
| format | Article |
| id | doaj.art-e53ded1506ff4e99b77fbad1cfb786cf |
| institution | Directory Open Access Journal |
| issn | 2309-608X |
| language | English |
| last_indexed | 2024-03-09T13:41:49Z |
| publishDate | 2022-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj.art-e53ded1506ff4e99b77fbad1cfb786cf2023-11-30T21:05:41ZengMDPI AGJournal of Fungi2309-608X2022-03-018331010.3390/jof8030310Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing HomesMing-Gene Tu0Chih-Chao Lin1Ya-Ting Chiang2Zi-Li Zhou3Li-Yun Hsieh4Kai-Ting Chen5Yin-Zhi Chen6Wen-Chi Cheng7Hsiu-Jung Lo8School of Dentistry, China Medical University, Taichung 404, TaiwanTaiwan Mycology Reference Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, TaiwanSchool of Dentistry, China Medical University, Taichung 404, TaiwanTaiwan Mycology Reference Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, TaiwanTaiwan Mycology Reference Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, TaiwanTaiwan Mycology Reference Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, TaiwanTaiwan Mycology Reference Center, National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli County 350, TaiwanGeneral Biologicals Corporation, Hsinchu 300, TaiwanSchool of Dentistry, China Medical University, Taichung 404, TaiwanMost yeasts causing infections in humans are part of commensal microflora and etiological agents of different infections when hosts become susceptible, usually due to becoming immunocompromised. The colonization of potentially pathogenic microbes in the oral cavity is increased by poor oral hygiene. This follow-up survey was conducted approximately two months after providing information on proper oral care at 10 nursing homes in Taiwan. Among the 117 of 165 residents colonized by yeasts, 67 were colonized by more than one yeast species. A total of 231 isolates comprising eight fungal genera and 25 species were identified. <i>Candida albicans</i> (44.6%) was the dominant species, followed by <i>Candida glabrata</i> (17.7%), <i>Candida parapsilosis</i> (8.7%), <i>Candida tropicalis</i> (7.8%), and <i>Candida pararugosa</i> (7.3%). Residents having a yeast colony-forming unit >10 (OR, 8.897; 95% CI 2.972–26.634; <i>p</i> < 0.001) or using a wheelchair (OR, 4.682; 95% CI 1.599–13.705; <i>p</i> = 0.005) were more likely to be colonized by multiple species. By comparing before and after oral-care education, dry mouth (OR, 3.199; 95% CI 1.448–7.068; <i>p</i> = 0.011) and having heart disease (OR, 2.681; 95% CI 1.068–6.732; <i>p</i> = 0.036) emerged as two independent risk factors for increased density of colonizing yeast.https://www.mdpi.com/2309-608X/8/3/310agingdenture wearerdry mouthelderlyyeast colonizationoral-care education |
| spellingShingle | Ming-Gene Tu Chih-Chao Lin Ya-Ting Chiang Zi-Li Zhou Li-Yun Hsieh Kai-Ting Chen Yin-Zhi Chen Wen-Chi Cheng Hsiu-Jung Lo Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes Journal of Fungi aging denture wearer dry mouth elderly yeast colonization oral-care education |
| title | Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes |
| title_full | Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes |
| title_fullStr | Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes |
| title_full_unstemmed | Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes |
| title_short | Distribution of Yeast Species and Risk Factors of Oral Colonization after Oral-Care Education among the Residents of Nursing Homes |
| title_sort | distribution of yeast species and risk factors of oral colonization after oral care education among the residents of nursing homes |
| topic | aging denture wearer dry mouth elderly yeast colonization oral-care education |
| url | https://www.mdpi.com/2309-608X/8/3/310 |
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