Emerging Approaches to Profile Accessible Chromatin from Formalin-Fixed Paraffin-Embedded Sections

Emerging Approaches to Profile Accessible Chromatin from Formalin-Fixed Paraffin-Embedded Sections

Nucleosomes are non-uniformly distributed across eukaryotic genomes, with stretches of ‘open’ chromatin strongly associated with transcriptionally active promoters and enhancers. Understanding chromatin accessibility patterns in normal tissue and how they are altered in pathologies can provide criti...

Full description

Bibliographic Details
Main Authors: Vishnu Udayakumaran Nair Sunitha Kumary, Bryan J. Venters, Karthikeyan Raman, Sagnik Sen, Pierre-Olivier Estève, Martis W. Cowles, Michael-Christopher Keogh, Sriharsa Pradhan
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Epigenomes
Subjects:
chromatin
FFPE
nucleosome
nucleosome-free region
nucleosome-depleted region
Online Access:https://www.mdpi.com/2075-4655/8/2/20

Internet

https://www.mdpi.com/2075-4655/8/2/20

Similar Items