A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice
Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight re...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-07-01
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| Series: | International Journal of Molecular Sciences |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1422-0067/24/13/11132 |
| _version_ | 1797591516574646272 |
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| author | Sacchin Arockiam Brittany Staniforth Sacha Kepreotis Annette Maznyczka Heerajnarain Bulluck |
| author_facet | Sacchin Arockiam Brittany Staniforth Sacha Kepreotis Annette Maznyczka Heerajnarain Bulluck |
| author_sort | Sacchin Arockiam |
| collection | DOAJ |
| description | Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight recent trials exploring antiplatelet therapy in atherosclerotic cardiovascular disease, but also in trials related to transcatheter aortic valve implantation and coronavirus disease 2019. Inevitably, the antithrombotic benefits of these drugs are accompanied by an increase in bleeding complications. Therefore, an individualised approach to weighing each patient’s thrombotic risk versus bleeding risk is imperative, in order to improve clinical outcomes. |
| first_indexed | 2024-03-11T01:38:34Z |
| format | Article |
| id | doaj.art-e54383880258447a8781f32f554999bd |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-11T01:38:34Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-e54383880258447a8781f32f554999bd2023-11-18T16:48:36ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-07-0124131113210.3390/ijms241311132A Contemporary Review of Antiplatelet Therapies in Current Clinical PracticeSacchin Arockiam0Brittany Staniforth1Sacha Kepreotis2Annette Maznyczka3Heerajnarain Bulluck4Yorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS2 3AX, UKYorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS2 3AX, UKYorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS2 3AX, UKYorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS2 3AX, UKYorkshire Heart Centre, Leeds General Infirmary, Leeds Teaching Hospitals NHS Trust, Leeds LS2 3AX, UKAntiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to summarise the common antiplatelet agents currently available, and their use in clinic practice. We not only highlight recent trials exploring antiplatelet therapy in atherosclerotic cardiovascular disease, but also in trials related to transcatheter aortic valve implantation and coronavirus disease 2019. Inevitably, the antithrombotic benefits of these drugs are accompanied by an increase in bleeding complications. Therefore, an individualised approach to weighing each patient’s thrombotic risk versus bleeding risk is imperative, in order to improve clinical outcomes.https://www.mdpi.com/1422-0067/24/13/11132antiplatelet therapyatherosclerotic vascular diseaseischaemic heart diseaseacute coronary syndromecoronary artery bypass graft surgerystroke |
| spellingShingle | Sacchin Arockiam Brittany Staniforth Sacha Kepreotis Annette Maznyczka Heerajnarain Bulluck A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice International Journal of Molecular Sciences antiplatelet therapy atherosclerotic vascular disease ischaemic heart disease acute coronary syndrome coronary artery bypass graft surgery stroke |
| title | A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice |
| title_full | A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice |
| title_fullStr | A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice |
| title_full_unstemmed | A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice |
| title_short | A Contemporary Review of Antiplatelet Therapies in Current Clinical Practice |
| title_sort | contemporary review of antiplatelet therapies in current clinical practice |
| topic | antiplatelet therapy atherosclerotic vascular disease ischaemic heart disease acute coronary syndrome coronary artery bypass graft surgery stroke |
| url | https://www.mdpi.com/1422-0067/24/13/11132 |
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