A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis
We report the case of a 31-year-old woman with 4 episodes of myelitis with pleocytosis, a positive Borrelia burgdorferi serology with positive antibody indices, and full recovery each time after antibiotic and steroid treatment, suggesting neuroborreliosis. We nevertheless believe that recurrent neu...
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| Format: | Article |
| Language: | English |
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Karger Publishers
2012-03-01
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| Series: | Case Reports in Neurology |
| Subjects: | |
| Online Access: | http://www.karger.com/Article/FullText/337223 |
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| author | P. Albrecht N. Henke H.C. Lehmann S. Macht H. Hefter N. Goebels C. Mackenzie T.A. Rupprecht V. Fingerle H.P. Hartung A. Methner |
| author_facet | P. Albrecht N. Henke H.C. Lehmann S. Macht H. Hefter N. Goebels C. Mackenzie T.A. Rupprecht V. Fingerle H.P. Hartung A. Methner |
| author_sort | P. Albrecht |
| collection | DOAJ |
| description | We report the case of a 31-year-old woman with 4 episodes of myelitis with pleocytosis, a positive Borrelia burgdorferi serology with positive antibody indices, and full recovery each time after antibiotic and steroid treatment, suggesting neuroborreliosis. We nevertheless believe that recurrent neuroborreliosis is improbable based on the levels of the chemokine CXCL13 in cerebrospinal fluid and favor the diagnosis of post-infectious autoimmune-mediated transverse myelitis possibly triggered by an initial neuroborreliosis as the cause of the relapses observed in our patient. We demonstrate the diagnostic steps and procedures which were important in the differential diagnosis of this unusual and challenging case. |
| first_indexed | 2024-12-23T20:30:50Z |
| format | Article |
| id | doaj.art-e5453ebfb2584f1397c1d7deafae11d1 |
| institution | Directory Open Access Journal |
| issn | 1662-680X |
| language | English |
| last_indexed | 2024-12-23T20:30:50Z |
| publishDate | 2012-03-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Neurology |
| spelling | doaj.art-e5453ebfb2584f1397c1d7deafae11d12022-12-21T17:32:15ZengKarger PublishersCase Reports in Neurology1662-680X2012-03-0141475310.1159/000337223337223A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent MyelitisP. AlbrechtN. HenkeH.C. LehmannS. MachtH. HefterN. GoebelsC. MackenzieT.A. RupprechtV. FingerleH.P. HartungA. MethnerWe report the case of a 31-year-old woman with 4 episodes of myelitis with pleocytosis, a positive Borrelia burgdorferi serology with positive antibody indices, and full recovery each time after antibiotic and steroid treatment, suggesting neuroborreliosis. We nevertheless believe that recurrent neuroborreliosis is improbable based on the levels of the chemokine CXCL13 in cerebrospinal fluid and favor the diagnosis of post-infectious autoimmune-mediated transverse myelitis possibly triggered by an initial neuroborreliosis as the cause of the relapses observed in our patient. We demonstrate the diagnostic steps and procedures which were important in the differential diagnosis of this unusual and challenging case.http://www.karger.com/Article/FullText/337223NeuroborreliosisBorrelia burgdorferiLyme borreliosisCerebrospinal fluidMyelitisCXCL13 |
| spellingShingle | P. Albrecht N. Henke H.C. Lehmann S. Macht H. Hefter N. Goebels C. Mackenzie T.A. Rupprecht V. Fingerle H.P. Hartung A. Methner A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis Case Reports in Neurology Neuroborreliosis Borrelia burgdorferi Lyme borreliosis Cerebrospinal fluid Myelitis CXCL13 |
| title | A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis |
| title_full | A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis |
| title_fullStr | A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis |
| title_full_unstemmed | A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis |
| title_short | A Case of Relapsing-Remitting Neuroborreliosis Challenges in the Differential Diagnosis of Recurrent Myelitis |
| title_sort | case of relapsing remitting neuroborreliosis challenges in the differential diagnosis of recurrent myelitis |
| topic | Neuroborreliosis Borrelia burgdorferi Lyme borreliosis Cerebrospinal fluid Myelitis CXCL13 |
| url | http://www.karger.com/Article/FullText/337223 |
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