Overexpression of Amyloid Precursor Protein Promotes the Onset of Seborrhoeic Keratosis and is Related to Skin Ageing
Seborrhoeic keratosis (SK) is an age-related skin disease. Amyloid precursor protein (APP) plays an important role in the pathogenesis of age-related Alzheimer’s disease. The aim of this study was to elucidate the expression characteristics of APP in SK tissues (n = 50), and explore whether the prod...
Main Authors: | Yuanying Li, Yu Wang, Wei Zhang, Leiwei Jiang, Wenming Zhou, Zhi Liu, Shijun Li, Hongguang Lu |
---|---|
Format: | Article |
Language: | English |
Published: |
Medical Journals Sweden
2018-03-01
|
Series: | Acta Dermato-Venereologica |
Subjects: | |
Online Access: |
https://www.medicaljournals.se/acta/content/html/10.2340/00015555-2911
|
Similar Items
-
Role of BACE1 in Alzheimer’s synaptic function
by: Brati Das, et al.
Published: (2017-08-01) -
Scaffold Morphing and In Silico Design of Potential BACE-1 (β-Secretase) Inhibitors: A Hope for a Newer Dawn in Anti-Alzheimer Therapeutics
by: Shiveena Bhatia, et al.
Published: (2023-08-01) -
Presenilin-1 interacts directly with the β-site amyloid protein precursor cleaving enzyme (BACE1)
by: Sébastien S Hébert, et al.
Published: (2003-08-01) -
Decreased expression of GGA3 Protein in Alzheimer's disease frontal cortex and increased co-distribution of BACE with the amyloid precursor protein
by: Claudia Santosa, et al.
Published: (2011-07-01) -
Glycosaminoglycans from <i>Litopenaeus vannamei</i> Inhibit the Alzheimer’s Disease β Secretase, BACE1
by: Courtney J. Mycroft-West, et al.
Published: (2021-04-01)