Diclofenac and metformin synergistic dose dependent inhibition of hamster fibrosarcoma, rescued with mebendazole

Diclofenac and metformin synergistic dose dependent inhibition of hamster fibrosarcoma, rescued with mebendazole

We examined whether combinig diclofenac and metformin in doses equivalent to human doses would synergize their anticancer activity on fibrosarcoma inoculated to hamsters and in vitro. Rescue experiment was performed to examine whether the prosurvival NF-κB stimulation by mebendazole can reverse anti...

Full description

Bibliographic Details
Main Authors: Dušica J. Popović, Kosta J. Popović, Dejan Miljković, Jovan K. Popović, Dušan Lalošević, Mihalj Poša, Zana Dolićanin, Ivan Čapo
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Diclofenac
Metformin
Mebendazole
NF-κB
Hamsters
Fibrosarcoma
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223013264

Internet

http://www.sciencedirect.com/science/article/pii/S0753332223013264

Similar Items