Glutathione-sensitive nanoparticles enhance the combined therapeutic effect of checkpoint kinase 1 inhibitor and cisplatin in prostate cancer

Prostate cancer (PCa) is the second most common malignant tumor among males. Traditional treatments for PCa, which include surgery and endocrine therapy, have shown limited success, and more effective therapies are needed. Cisplatin (DDP) is an approved chemotherapeutic drug that causes DNA damage i...

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Bibliographic Details
Main Authors: Shirong Peng, Xinyu Zhang, Hao Huang, Bisheng Cheng, Zhi Xiong, Tao Du, Jun Wu, Hai Huang
Format: Article
Language:English
Published: AIP Publishing LLC 2022-12-01
Series:APL Bioengineering
Online Access:http://dx.doi.org/10.1063/5.0126095

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