Localized renal cell carcinoma management: an update
OBJECTIVE: To review the current modalities of treatment for localized renal cell carcinoma. MATERIALS AND METHODS: A literature search for keywords: renal cell carcinoma, radical nephrectomy, nephron sparing surgery, minimally invasive surgery, and cryoablation was performed for the years 2000 thro...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Sociedade Brasileira de Urologia
2008-12-01
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| Series: | International Brazilian Journal of Urology |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382008000600002 |
| _version_ | 1818010005828272128 |
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| author | Flavio L. Heldwein T. Casey Mccullough Carlos A. V. Souto Marc Galiano Eric Barret |
| author_facet | Flavio L. Heldwein T. Casey Mccullough Carlos A. V. Souto Marc Galiano Eric Barret |
| author_sort | Flavio L. Heldwein |
| collection | DOAJ |
| description | OBJECTIVE: To review the current modalities of treatment for localized renal cell carcinoma. MATERIALS AND METHODS: A literature search for keywords: renal cell carcinoma, radical nephrectomy, nephron sparing surgery, minimally invasive surgery, and cryoablation was performed for the years 2000 through 2008. The most relevant publications were examined. RESULTS: New epidemiologic data and current treatment of renal cancer were covered. Concerning the treatment of clinically localized disease, the literature supports the standardization of partial nephrectomy and laparoscopic approaches as therapeutic options with better functional results and oncologic success comparable to standard radical resection. Promising initial results are now available for minimally invasive therapies, such as cryotherapy and radiofrequency ablation. Active surveillance has been reported with acceptable results, including for those who are poor surgical candidates. CONCLUSIONS: This review covers current advances in radical and conservative treatments of localized kidney cancer. The current status of nephron-sparing surgery, ablative therapies, and active surveillance based on natural history has resulted in great progress in the management of localized renal cell carcinoma. |
| first_indexed | 2024-04-14T05:49:56Z |
| format | Article |
| id | doaj.art-e54dc3fdcf014602aec9e77f69e89017 |
| institution | Directory Open Access Journal |
| issn | 1677-5538 1677-6119 |
| language | English |
| last_indexed | 2024-04-14T05:49:56Z |
| publishDate | 2008-12-01 |
| publisher | Sociedade Brasileira de Urologia |
| record_format | Article |
| series | International Brazilian Journal of Urology |
| spelling | doaj.art-e54dc3fdcf014602aec9e77f69e890172022-12-22T02:09:10ZengSociedade Brasileira de UrologiaInternational Brazilian Journal of Urology1677-55381677-61192008-12-0134667669010.1590/S1677-55382008000600002Localized renal cell carcinoma management: an updateFlavio L. HeldweinT. Casey McculloughCarlos A. V. SoutoMarc GalianoEric BarretOBJECTIVE: To review the current modalities of treatment for localized renal cell carcinoma. MATERIALS AND METHODS: A literature search for keywords: renal cell carcinoma, radical nephrectomy, nephron sparing surgery, minimally invasive surgery, and cryoablation was performed for the years 2000 through 2008. The most relevant publications were examined. RESULTS: New epidemiologic data and current treatment of renal cancer were covered. Concerning the treatment of clinically localized disease, the literature supports the standardization of partial nephrectomy and laparoscopic approaches as therapeutic options with better functional results and oncologic success comparable to standard radical resection. Promising initial results are now available for minimally invasive therapies, such as cryotherapy and radiofrequency ablation. Active surveillance has been reported with acceptable results, including for those who are poor surgical candidates. CONCLUSIONS: This review covers current advances in radical and conservative treatments of localized kidney cancer. The current status of nephron-sparing surgery, ablative therapies, and active surveillance based on natural history has resulted in great progress in the management of localized renal cell carcinoma.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382008000600002renal cell carcinomatreatmentnephrectomysurgical proceduresminimally invasive |
| spellingShingle | Flavio L. Heldwein T. Casey Mccullough Carlos A. V. Souto Marc Galiano Eric Barret Localized renal cell carcinoma management: an update International Brazilian Journal of Urology renal cell carcinoma treatment nephrectomy surgical procedures minimally invasive |
| title | Localized renal cell carcinoma management: an update |
| title_full | Localized renal cell carcinoma management: an update |
| title_fullStr | Localized renal cell carcinoma management: an update |
| title_full_unstemmed | Localized renal cell carcinoma management: an update |
| title_short | Localized renal cell carcinoma management: an update |
| title_sort | localized renal cell carcinoma management an update |
| topic | renal cell carcinoma treatment nephrectomy surgical procedures minimally invasive |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1677-55382008000600002 |
| work_keys_str_mv | AT flaviolheldwein localizedrenalcellcarcinomamanagementanupdate AT tcaseymccullough localizedrenalcellcarcinomamanagementanupdate AT carlosavsouto localizedrenalcellcarcinomamanagementanupdate AT marcgaliano localizedrenalcellcarcinomamanagementanupdate AT ericbarret localizedrenalcellcarcinomamanagementanupdate |