Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability
People with peripheral neuropathy (PN) are at risk of falling. Many people with PN have comorbid cognitive impairment, an independent risk factor of falls, which may further increase the risk of falling in people with PN. However, the negative synergic effect of those factors is yet to be reported....
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-02-01
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| Series: | Sensors |
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| Online Access: | https://www.mdpi.com/1424-8220/20/5/1328 |
| _version_ | 1811303285713272832 |
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| author | Gu Eon Kang Jacqueline Yang Bijan Najafi |
| author_facet | Gu Eon Kang Jacqueline Yang Bijan Najafi |
| author_sort | Gu Eon Kang |
| collection | DOAJ |
| description | People with peripheral neuropathy (PN) are at risk of falling. Many people with PN have comorbid cognitive impairment, an independent risk factor of falls, which may further increase the risk of falling in people with PN. However, the negative synergic effect of those factors is yet to be reported. We investigated whether the presence of cognitive impairment exacerbates the risk of falls in people with PN by measuring gait variability during single-task walking and dual-task walking. Forty-four adults with PN were recruited. Based on the Montreal Cognitive Assessment (MoCA) scores, 19 and 25 subjects were cognitively impaired and intact, respectively. We measured coefficients of variation of gait speed, stride length, and stride time using validated body-worn sensors. During single-task walking, no between-group differences were observed (all <i>p</i> > 0.05). During dual-task walking, between-group differences were significant for gait variability for gait speed and stride length (51.4% and 71.1%, respectively; <i>p</i> = 0.014 and 0.011, respectively). MoCA scores were significantly correlated with gait variability for gait speed (<i>r</i> = 0.319, <i>p</i> = 0.035) and stride length (<i>r</i> = 0.367, <i>p</i> = 0.014) during dual-task walking. Our findings suggest that the presence of cognitive impairment exacerbates the risk of falls in people with PN. |
| first_indexed | 2024-04-13T07:44:12Z |
| format | Article |
| id | doaj.art-e55030a99e0f4f7b98da1d53882f27db |
| institution | Directory Open Access Journal |
| issn | 1424-8220 |
| language | English |
| last_indexed | 2024-04-13T07:44:12Z |
| publishDate | 2020-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Sensors |
| spelling | doaj.art-e55030a99e0f4f7b98da1d53882f27db2022-12-22T02:55:46ZengMDPI AGSensors1424-82202020-02-01205132810.3390/s20051328s20051328Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait VariabilityGu Eon Kang0Jacqueline Yang1Bijan Najafi2Interdisciplinary Consortium on Advanced Motion Performance (iCAMP), Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USAInterdisciplinary Consortium on Advanced Motion Performance (iCAMP), Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USAInterdisciplinary Consortium on Advanced Motion Performance (iCAMP), Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX 77030, USAPeople with peripheral neuropathy (PN) are at risk of falling. Many people with PN have comorbid cognitive impairment, an independent risk factor of falls, which may further increase the risk of falling in people with PN. However, the negative synergic effect of those factors is yet to be reported. We investigated whether the presence of cognitive impairment exacerbates the risk of falls in people with PN by measuring gait variability during single-task walking and dual-task walking. Forty-four adults with PN were recruited. Based on the Montreal Cognitive Assessment (MoCA) scores, 19 and 25 subjects were cognitively impaired and intact, respectively. We measured coefficients of variation of gait speed, stride length, and stride time using validated body-worn sensors. During single-task walking, no between-group differences were observed (all <i>p</i> > 0.05). During dual-task walking, between-group differences were significant for gait variability for gait speed and stride length (51.4% and 71.1%, respectively; <i>p</i> = 0.014 and 0.011, respectively). MoCA scores were significantly correlated with gait variability for gait speed (<i>r</i> = 0.319, <i>p</i> = 0.035) and stride length (<i>r</i> = 0.367, <i>p</i> = 0.014) during dual-task walking. Our findings suggest that the presence of cognitive impairment exacerbates the risk of falls in people with PN.https://www.mdpi.com/1424-8220/20/5/1328cognitive impairmentdiabetic peripheral neuropathychemotherapy-induced peripheral neuropathysingle-task walkingdual-task walkinggait variabilitybody-worn sensors |
| spellingShingle | Gu Eon Kang Jacqueline Yang Bijan Najafi Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability Sensors cognitive impairment diabetic peripheral neuropathy chemotherapy-induced peripheral neuropathy single-task walking dual-task walking gait variability body-worn sensors |
| title | Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability |
| title_full | Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability |
| title_fullStr | Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability |
| title_full_unstemmed | Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability |
| title_short | Does the Presence of Cognitive Impairment Exacerbate the Risk of Falls in People with Peripheral Neuropathy? An Application of Body-Worn Inertial Sensors to Measure Gait Variability |
| title_sort | does the presence of cognitive impairment exacerbate the risk of falls in people with peripheral neuropathy an application of body worn inertial sensors to measure gait variability |
| topic | cognitive impairment diabetic peripheral neuropathy chemotherapy-induced peripheral neuropathy single-task walking dual-task walking gait variability body-worn sensors |
| url | https://www.mdpi.com/1424-8220/20/5/1328 |
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