Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases
Abstract Background Pericoronal radiolucent lesions are a common radiographic finding, but it is rare that they occur in multiple forms. Multiple calcifying hyperplastic dental follicles (MCHDF) are entities with few cases described to date; nevertheless, they appear to have a very particular phenot...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-06-01
|
| Series: | BMC Oral Health |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12903-020-01146-y |
| _version_ | 1818517158367330304 |
|---|---|
| author | Israel Guardado-Luevanos Anna Jazmine Haro Marisol Godínez-Rubí Jorge Alejandro Puente-de los Santos Jaime Aguirre-Macías Diana Paloma Soltero-Chávez Miguel Padilla-Rosas Mario Nava-Villalba |
| author_facet | Israel Guardado-Luevanos Anna Jazmine Haro Marisol Godínez-Rubí Jorge Alejandro Puente-de los Santos Jaime Aguirre-Macías Diana Paloma Soltero-Chávez Miguel Padilla-Rosas Mario Nava-Villalba |
| author_sort | Israel Guardado-Luevanos |
| collection | DOAJ |
| description | Abstract Background Pericoronal radiolucent lesions are a common radiographic finding, but it is rare that they occur in multiple forms. Multiple calcifying hyperplastic dental follicles (MCHDF) are entities with few cases described to date; nevertheless, they appear to have a very particular phenotypic pattern. Cases presentation Case 1: A 10-year-old male was evaluated radiographically, revealing four impacted canines, each accompanied by unilocular pericoronal radiolucency. Case 2: A 16-year-old male was planning orthodontic treatment; following his radiological evaluation all third molars were found to be accompanied with pericoronal radiolucencies. Enucleation, and third molar removal along with the pericoronal tissue were the respective treatments. Microscopically, in both cases, the specimens shown odontogenic epithelium, and type I and II calcifications in the hyperplastic follicles, all these characteristics were consistent with MCHDF. Conclusion Although MCHDF are a rare entity, they must be considered in the differential diagnosis of multiple pericoronal lesions. Under the light of the current evidence, the histological findings may be relatively heterogeneous, but their integration with both the clinical data, which are apparently particular, and with the radiographic characteristics, can lead to a definitive diagnosis. |
| first_indexed | 2024-12-11T00:52:25Z |
| format | Article |
| id | doaj.art-e550356d900343d88b733913be39065a |
| institution | Directory Open Access Journal |
| issn | 1472-6831 |
| language | English |
| last_indexed | 2024-12-11T00:52:25Z |
| publishDate | 2020-06-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj.art-e550356d900343d88b733913be39065a2022-12-22T01:26:36ZengBMCBMC Oral Health1472-68312020-06-0120111010.1186/s12903-020-01146-yMultiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two casesIsrael Guardado-Luevanos0Anna Jazmine Haro1Marisol Godínez-Rubí2Jorge Alejandro Puente-de los Santos3Jaime Aguirre-Macías4Diana Paloma Soltero-Chávez5Miguel Padilla-Rosas6Mario Nava-Villalba7Master’s Program in Oral Pathology and Medicine, Department of Integral Dental Clinics, University Centre of Health Sciences, Universidad de GuadalajaraLaboratory of Pathology Research, Department of Microbiology and Pathology, University Centre of Health Sciences, Universidad de GuadalajaraLaboratory of Pathology Research, Department of Microbiology and Pathology, University Centre of Health Sciences, Universidad de GuadalajaraMaxillofacial Surgery Service, Hospital General de Zapopan O.P.D.Inova Dental ClinicNucleo Dental, Dental ClinicMaster’s Program in Oral Pathology and Medicine, Department of Integral Dental Clinics, University Centre of Health Sciences, Universidad de GuadalajaraLaboratory of Pathology Research, Department of Microbiology and Pathology, University Centre of Health Sciences, Universidad de GuadalajaraAbstract Background Pericoronal radiolucent lesions are a common radiographic finding, but it is rare that they occur in multiple forms. Multiple calcifying hyperplastic dental follicles (MCHDF) are entities with few cases described to date; nevertheless, they appear to have a very particular phenotypic pattern. Cases presentation Case 1: A 10-year-old male was evaluated radiographically, revealing four impacted canines, each accompanied by unilocular pericoronal radiolucency. Case 2: A 16-year-old male was planning orthodontic treatment; following his radiological evaluation all third molars were found to be accompanied with pericoronal radiolucencies. Enucleation, and third molar removal along with the pericoronal tissue were the respective treatments. Microscopically, in both cases, the specimens shown odontogenic epithelium, and type I and II calcifications in the hyperplastic follicles, all these characteristics were consistent with MCHDF. Conclusion Although MCHDF are a rare entity, they must be considered in the differential diagnosis of multiple pericoronal lesions. Under the light of the current evidence, the histological findings may be relatively heterogeneous, but their integration with both the clinical data, which are apparently particular, and with the radiographic characteristics, can lead to a definitive diagnosis.http://link.springer.com/article/10.1186/s12903-020-01146-yPericoronal radiolucenciesPericoronal lesionsMultiple jaw radiolucencies |
| spellingShingle | Israel Guardado-Luevanos Anna Jazmine Haro Marisol Godínez-Rubí Jorge Alejandro Puente-de los Santos Jaime Aguirre-Macías Diana Paloma Soltero-Chávez Miguel Padilla-Rosas Mario Nava-Villalba Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases BMC Oral Health Pericoronal radiolucencies Pericoronal lesions Multiple jaw radiolucencies |
| title | Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases |
| title_full | Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases |
| title_fullStr | Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases |
| title_full_unstemmed | Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases |
| title_short | Multiple calcifying hyperplastic dental follicles: a major diagnostic consideration in multiple pericoronal lesions - report of two cases |
| title_sort | multiple calcifying hyperplastic dental follicles a major diagnostic consideration in multiple pericoronal lesions report of two cases |
| topic | Pericoronal radiolucencies Pericoronal lesions Multiple jaw radiolucencies |
| url | http://link.springer.com/article/10.1186/s12903-020-01146-y |
| work_keys_str_mv | AT israelguardadoluevanos multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT annajazmineharo multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT marisolgodinezrubi multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT jorgealejandropuentedelossantos multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT jaimeaguirremacias multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT dianapalomasolterochavez multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT miguelpadillarosas multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases AT marionavavillalba multiplecalcifyinghyperplasticdentalfolliclesamajordiagnosticconsiderationinmultiplepericoronallesionsreportoftwocases |