Co-administration of metformin and gallic acid modulates JAK/STAT signaling pathway and glutathione metabolism in fructose-fed streptozotocin diabetic Rats

Co-administration of metformin and gallic acid modulates JAK/STAT signaling pathway and glutathione metabolism in fructose-fed streptozotocin diabetic Rats

Background: Incidence of diabetes Mellitus (DM) is on the rise with each passing year in spite of available therapies in the management of DM. Metformin, a standard antidiabetic drug, and gallic acid (GA) are some of the compounds with established antidiabetic properties. However, there is dearth of...

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Bibliographic Details
Main Authors: Olusola Olalekan Elekofehinti, Esther Opeyemi Ariyo, Opeyemi Iwaloye, Tajudeen O Obafemi
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Phytomedicine Plus
Subjects:
Gallic acid
Metformin
Inflammatory genes
Diabetes mellitus
Janus kinase
Signal transducer and activator of transcription
Online Access:http://www.sciencedirect.com/science/article/pii/S2667031321001639

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