Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae

Three Capsular Polysaccharide Synthesis-Related Glucosyltransferases, GT-1, GT-2 and WcaJ, Are Associated With Virulence and Phage Sensitivity of Klebsiella pneumoniae

Klebsiella pneumoniae (K. pneumoniae) spp. are important nosocomial and community-acquired opportunistic pathogens, which cause various infections. We observed that K. pneumoniae strain K7 abruptly mutates to rough-type phage-resistant phenotype upon treatment with phage GH-K3. In the present study,...

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Bibliographic Details
Main Authors: Ruopeng Cai, Gang Wang, Shuai Le, Mei Wu, Mengjun Cheng, Zhimin Guo, Yalu Ji, Hengyu Xi, Caijun Zhao, Xinwu Wang, Yibing Xue, Zijing Wang, Hao Zhang, Yunhe Fu, Changjiang Sun, Xin Feng, Liancheng Lei, Yongjun Yang, Sadeeq ur Rahman, Xiaoyun Liu, Wenyu Han, Jingmin Gu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Microbiology
Subjects:
Klebsiella pneumoniae
phage resistance
virulence
glucosyltransferase (GT)
WcaJ
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01189/full

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