A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016
<h4>Aims</h4> The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32–86 years old women and men. <h4>Methods</h4> Data were retrieved from the 20...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2022-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791505/?tool=EBI |
| _version_ | 1798031842143633408 |
|---|---|
| author | Saija Mikkilä Jonas Johansson Anna Nordström Peter Nordström Nina Emaus Bjørn Helge Handegård Bente Morseth Boye Welde |
| author_facet | Saija Mikkilä Jonas Johansson Anna Nordström Peter Nordström Nina Emaus Bjørn Helge Handegård Bente Morseth Boye Welde |
| author_sort | Saija Mikkilä |
| collection | DOAJ |
| description | <h4>Aims</h4> The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32–86 years old women and men. <h4>Methods</h4> Data were retrieved from the 2001, 2007–2008, and 2015–2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical activity was assessed by the four-level Saltin-Grimby Physical Activity Level Scale which refers to physical exertion in the past twelve months. Hip aBMD was assessed by Dual-Energy X-ray Absorptiometry. Linear Mixed Model analysis was used to examine long-term associations between physical activity and hip aBMD (n = 6324). In addition, the annual change in hip aBMD was analyzed in a subsample of 3199 participants. <h4>Results</h4> Physical activity was significantly and positively associated with total hip aBMD in the overall cohort (p<0.005). Participants who reported vigorous activity had 28.20 mg/cm2 higher aBMD than those who were inactive (95% CI 14.71; 41.69, controlled for confounders), and even light physical activity was associated with higher aBMD than inactivity (8.32 mg/cm2, 95% CI 4.89; 11.76). Associations between physical activity and femoral neck aBMD yielded similar results. Hip aBMD decreased with age in both sexes, although more prominently in women. From 2001 to 2007–2008, aBMD changed by –5.76 mg/cm2 per year (95% CI –6.08; –5.44) in women, and –2.31 mg/cm2 (95% CI –2.69; –1.93), in men. From 2007–2008 to 2015–2016, the change was –4.45 mg/cm2 per year (95% CI –4.84; –4.06) in women, and –1.45 mg/cm2 (95% CI –1.92; –0.98) in men. <h4>Conclusions</h4> In this cohort of adult men and women, physical activity levels were positively associated with hip aBMD in a dose-response relationship. Hip aBMD decreased with age, although more pronounced in women than men. |
| first_indexed | 2024-04-11T20:03:03Z |
| format | Article |
| id | doaj.art-e5621bcddf214438b1cc31f823651463 |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-04-11T20:03:03Z |
| publishDate | 2022-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-e5621bcddf214438b1cc31f8236514632022-12-22T04:05:31ZengPublic Library of Science (PLoS)PLoS ONE1932-62032022-01-01171A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016Saija MikkiläJonas JohanssonAnna NordströmPeter NordströmNina EmausBjørn Helge HandegårdBente MorsethBoye Welde<h4>Aims</h4> The aim was to investigate the long-term association between leisure time physical activity and hip areal bone mineral density (aBMD), in addition to change in hip aBMD over time, in 32–86 years old women and men. <h4>Methods</h4> Data were retrieved from the 2001, 2007–2008, and 2015–2016 surveys of the Tromsø Study, a longitudinal population study in Norway. Leisure time physical activity was assessed by the four-level Saltin-Grimby Physical Activity Level Scale which refers to physical exertion in the past twelve months. Hip aBMD was assessed by Dual-Energy X-ray Absorptiometry. Linear Mixed Model analysis was used to examine long-term associations between physical activity and hip aBMD (n = 6324). In addition, the annual change in hip aBMD was analyzed in a subsample of 3199 participants. <h4>Results</h4> Physical activity was significantly and positively associated with total hip aBMD in the overall cohort (p<0.005). Participants who reported vigorous activity had 28.20 mg/cm2 higher aBMD than those who were inactive (95% CI 14.71; 41.69, controlled for confounders), and even light physical activity was associated with higher aBMD than inactivity (8.32 mg/cm2, 95% CI 4.89; 11.76). Associations between physical activity and femoral neck aBMD yielded similar results. Hip aBMD decreased with age in both sexes, although more prominently in women. From 2001 to 2007–2008, aBMD changed by –5.76 mg/cm2 per year (95% CI –6.08; –5.44) in women, and –2.31 mg/cm2 (95% CI –2.69; –1.93), in men. From 2007–2008 to 2015–2016, the change was –4.45 mg/cm2 per year (95% CI –4.84; –4.06) in women, and –1.45 mg/cm2 (95% CI –1.92; –0.98) in men. <h4>Conclusions</h4> In this cohort of adult men and women, physical activity levels were positively associated with hip aBMD in a dose-response relationship. Hip aBMD decreased with age, although more pronounced in women than men.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791505/?tool=EBI |
| spellingShingle | Saija Mikkilä Jonas Johansson Anna Nordström Peter Nordström Nina Emaus Bjørn Helge Handegård Bente Morseth Boye Welde A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 PLoS ONE |
| title | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 |
| title_full | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 |
| title_fullStr | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 |
| title_full_unstemmed | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 |
| title_short | A 15-year follow-up study of hip bone mineral density and associations with leisure time physical activity. The Tromsø Study 2001–2016 |
| title_sort | 15 year follow up study of hip bone mineral density and associations with leisure time physical activity the tromso study 2001 2016 |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8791505/?tool=EBI |
| work_keys_str_mv | AT saijamikkila a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT jonasjohansson a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT annanordstrom a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT peternordstrom a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT ninaemaus a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT bjørnhelgehandegard a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT bentemorseth a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT boyewelde a15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT saijamikkila 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT jonasjohansson 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT annanordstrom 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT peternordstrom 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT ninaemaus 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT bjørnhelgehandegard 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT bentemorseth 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 AT boyewelde 15yearfollowupstudyofhipbonemineraldensityandassociationswithleisuretimephysicalactivitythetromsøstudy20012016 |