Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance

Adenoids (nasopharyngeal tonsils), being part of Waldeyer’s ring, are masses of lymphoid tissues located at the junction of the roof and the posterior wall of the nasopharynx. Adenoids play an important role in the development of the immune system and serve as a defence against infections, being the...

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Main Authors: Artur Niedzielski, Lechosław Paweł Chmielik, Grażyna Mielnik-Niedzielska, Anna Kasprzyk, Joanna Bogusławska
Format: Article
Language:English
Published: BMJ Publishing Group 2023-12-01
Series:BMJ Paediatrics Open
Online Access:https://bmjpaedsopen.bmj.com/content/7/1/e001710.full
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author Artur Niedzielski
Lechosław Paweł Chmielik
Grażyna Mielnik-Niedzielska
Anna Kasprzyk
Joanna Bogusławska
author_facet Artur Niedzielski
Lechosław Paweł Chmielik
Grażyna Mielnik-Niedzielska
Anna Kasprzyk
Joanna Bogusławska
author_sort Artur Niedzielski
collection DOAJ
description Adenoids (nasopharyngeal tonsils), being part of Waldeyer’s ring, are masses of lymphoid tissues located at the junction of the roof and the posterior wall of the nasopharynx. Adenoids play an important role in the development of the immune system and serve as a defence against infections, being the first organs that come into contact with respiratory and digestive antigens. The causes of adenoid hypertrophy are not fully known. They are most likely associated with aberrant immune reactions, infections, environmental exposures and hormonal or genetic factors. The aim of this review is to summarise the current knowledge of adenoid hypertrophy in children and associated diseases. Adenoid hypertrophy has many clinical manifestations that are frequent in the paediatric population and is accompanied by various comorbidities.
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spelling doaj.art-e5643d63b0d349c0abfd3ffed6abf6272024-01-02T17:30:08ZengBMJ Publishing GroupBMJ Paediatrics Open2399-97722023-12-017110.1136/bmjpo-2022-001710Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevanceArtur Niedzielski0Lechosław Paweł Chmielik1Grażyna Mielnik-Niedzielska2Anna Kasprzyk3Joanna Bogusławska4Department of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, PolandDepartment of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, PolandDepartment of Pediatric Otolaryngology, Medical University of Lublin, Lublin, PolandDepartment of Pediatric Otolaryngology, Centre of Postgraduate Medical Education, Warszawa, PolandDepartment of Biochemistry and Molecular Biology, Centre of Postgraduate Medical Education, Warszawa, PolandAdenoids (nasopharyngeal tonsils), being part of Waldeyer’s ring, are masses of lymphoid tissues located at the junction of the roof and the posterior wall of the nasopharynx. Adenoids play an important role in the development of the immune system and serve as a defence against infections, being the first organs that come into contact with respiratory and digestive antigens. The causes of adenoid hypertrophy are not fully known. They are most likely associated with aberrant immune reactions, infections, environmental exposures and hormonal or genetic factors. The aim of this review is to summarise the current knowledge of adenoid hypertrophy in children and associated diseases. Adenoid hypertrophy has many clinical manifestations that are frequent in the paediatric population and is accompanied by various comorbidities.https://bmjpaedsopen.bmj.com/content/7/1/e001710.full
spellingShingle Artur Niedzielski
Lechosław Paweł Chmielik
Grażyna Mielnik-Niedzielska
Anna Kasprzyk
Joanna Bogusławska
Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
BMJ Paediatrics Open
title Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
title_full Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
title_fullStr Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
title_full_unstemmed Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
title_short Adenoid hypertrophy in children: a narrative review of pathogenesis and clinical relevance
title_sort adenoid hypertrophy in children a narrative review of pathogenesis and clinical relevance
url https://bmjpaedsopen.bmj.com/content/7/1/e001710.full
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