Berberine Facilitates Extinction and Prevents the Return of Fear

Berberine Facilitates Extinction and Prevents the Return of Fear

Exposure to a catastrophic event or intense stimulation can trigger fear memories, and the threatening memories persist even over a lifetime. Exposure therapy is based on extinction learning and is widely used to treat fear-related disorders, but its effect on remote fear memory is modest. Berberine...

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Bibliographic Details
Main Authors: Shihao Huang, Yu Zhou, Feilong Wu, Cuijie Shi, He Yan, Liangpei Chen, Chang Yang, Yixiao Luo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
berberine
extinction
fear memory
contextual fear conditioning
PTSD
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.748995/full

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