Enhanced apoptosis of HCT116 colon cancer cells treated with extracts from Calotropis gigantea stem bark by starvation

Enhanced apoptosis of HCT116 colon cancer cells treated with extracts from Calotropis gigantea stem bark by starvation

Calotropis gigantea stem bark extract, particularly the dichloromethane fraction (CGDCM), demonstrated the most potent antiproliferative effects on hepatocellular carcinoma HepG2 and colorectal HCT116 cells. The current study focused on enhancing the effectiveness of cancer treatment with CGDCM at c...

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Bibliographic Details
Main Authors: Orakot Simanurak, Dumrongsak Pekthong, Julintorn Somran, Apirath Wangteeraprasert, Metawee Srikummool, Naphat Kaewpaeng, Supawadee Parhira, Piyarat Srisawang
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Heliyon
Subjects:
Nutritional starvation
Colon cancer cells
Calotropis gigantea stem bark extract
Apoptosis
Reactive oxygen species
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023052210

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