Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits
Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, par...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-12-01
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| Series: | Frontiers in Physiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2020.602748/full |
| _version_ | 1818919568006971392 |
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| author | Yong Ryoul Yang Ki-Sun Kwon Ki-Sun Kwon |
| author_facet | Yong Ryoul Yang Ki-Sun Kwon Ki-Sun Kwon |
| author_sort | Yong Ryoul Yang |
| collection | DOAJ |
| description | Regular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise. |
| first_indexed | 2024-12-20T01:07:55Z |
| format | Article |
| id | doaj.art-e57186330cbc4ad88a71e91883e05884 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-20T01:07:55Z |
| publishDate | 2020-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-e57186330cbc4ad88a71e91883e058842022-12-21T19:58:46ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2020-12-011110.3389/fphys.2020.602748602748Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health BenefitsYong Ryoul Yang0Ki-Sun Kwon1Ki-Sun Kwon2Aging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South KoreaAging Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, South KoreaDepartment of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, South KoreaRegular exercise has a myriad of health benefits. An increase in circulating exercise factors following exercise is a critical physiological response. Numerous studies have shown that exercise factors released from tissues during physical activity may contribute to health benefits via autocrine, paracrine, and endocrine mechanisms. Myokines, classified as proteins secreted from skeletal muscle, are representative exercise factors. The roles of myokines have been demonstrated in a variety of exercise-related functions linked to health benefits. In addition to myokines, metabolites are also exercise factors. Exercise changes the levels of various metabolites via metabolic reactions. Several studies have identified exercise-induced metabolites that positively influence organ functions. Here, we provide an overview of selected metabolites secreted into the circulation upon exercise.https://www.frontiersin.org/articles/10.3389/fphys.2020.602748/fullexercisemetabolitesalpha-ketoglutarate (α-KG)beta-aminoisobutyric acid (BAIBA)kynurenic acid (KYNA)β-hydroxybutyrate (BHB) |
| spellingShingle | Yong Ryoul Yang Ki-Sun Kwon Ki-Sun Kwon Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits Frontiers in Physiology exercise metabolites alpha-ketoglutarate (α-KG) beta-aminoisobutyric acid (BAIBA) kynurenic acid (KYNA) β-hydroxybutyrate (BHB) |
| title | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
| title_full | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
| title_fullStr | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
| title_full_unstemmed | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
| title_short | Potential Roles of Exercise-Induced Plasma Metabolites Linking Exercise to Health Benefits |
| title_sort | potential roles of exercise induced plasma metabolites linking exercise to health benefits |
| topic | exercise metabolites alpha-ketoglutarate (α-KG) beta-aminoisobutyric acid (BAIBA) kynurenic acid (KYNA) β-hydroxybutyrate (BHB) |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2020.602748/full |
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