Clinical Significance of Urine Heparanase in Bladder Cancer Progression
Heparanase is an endo-β-glucuronidase capable of cleaving heparan sulfate (HS), an activity implicated in tumor metastasis. Heparanase expression is upregulated in primary human tumors, correlating with reduced post operative survival and elevated microvessel density. An ELISA method was used to qua...
| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | 論文 |
| 言語: | English |
| 出版事項: |
Elsevier
2008-02-01
|
| シリーズ: | Neoplasia: An International Journal for Oncology Research |
| オンライン･アクセス: | http://www.sciencedirect.com/science/article/pii/S1476558608800589 |