Clinical Significance of Urine Heparanase in Bladder Cancer Progression

Heparanase is an endo-β-glucuronidase capable of cleaving heparan sulfate (HS), an activity implicated in tumor metastasis. Heparanase expression is upregulated in primary human tumors, correlating with reduced post operative survival and elevated microvessel density. An ELISA method was used to qua...

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Bibliografische gegevens
Hoofdauteurs: Itay Shafat, Dov Pode, Tamar Peretz, Neta Ilan, Israel Vlodavsky, Nisman Benjamin
Formaat: Artikel
Taal:English
Gepubliceerd in: Elsevier 2008-02-01
Reeks:Neoplasia: An International Journal for Oncology Research
Online toegang:http://www.sciencedirect.com/science/article/pii/S1476558608800589