Glycyrrhizin Alleviates Neuroinflammation and Memory Deficit Induced by Systemic Lipopolysaccharide Treatment in Mice

Glycyrrhizin Alleviates Neuroinflammation and Memory Deficit Induced by Systemic Lipopolysaccharide Treatment in Mice

The present study investigated the effects of glycyrrhizin (GRZ) on neuroinflammation and memory deficit in systemic lipopolysaccharide (LPS)-treated C57BL/6 mice. Varying doses of GRZ was orally administered (10, 30, or 50 mg/kg) once a day for 3 days before the LPS (3 mg/kg) injection. At 24 h aft...

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Bibliographic Details
Main Authors: Jeong-Ho Song, Ju-Won Lee, Beomsoo Shim, Chang-Yeol Lee, Sooyong Choi, Chulhun Kang, Nak-Won Sohn, Jung-Won Shin
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Molecules
Subjects:
glycyrrhizin
neuroinflammation
memory deficit
microglial activation
Online Access:http://www.mdpi.com/1420-3049/18/12/15788

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