Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis

Gestational Hypothyroxinemia Affects Its Offspring With a Reduced Suppressive Capacity Impairing the Outcome of the Experimental Autoimmune Encephalomyelitis

Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypothyroidism increases the severity of experimental...

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Bibliographic Details
Main Authors: Henny Haensgen, Eduardo Albornoz, María C. Opazo, Katherinne Bugueño, Evelyn Liliana Jara Fernández, Rebecca Binzberger, Tomás Rivero-Castillo, Luis F. Venegas Salas, Felipe Simon, Claudio Cabello-Verrugio, Alvaro A. Elorza, Alexis M. Kalergis, Susan M. Bueno, Claudia A. Riedel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
hypothyroxinemia
T regulatory cells
multiple sclerosis
pregnancy
experimental autoimmune encephalomyelitis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01257/full

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